Anticorps TACC3 (D-2): sc-48368
- L'Anticorps TACC3 (D-2) est un monoclonal de souris IgG1 κ, cité dans 5 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 1-300 de TACC3 d'origine human
- recommandé pour la détection de TACC3 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps TACC3 (D-2) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps TACC3 (D-2) (voir Informations pour la commande ci-dessous).
TACC1 (transforming acidic coiled coil gene 1) is one of three TACC family members, which are thought to be involved in breast tumorigenesis. TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2 and TACC3, map very closely to the corresponding FGFR1, FGFR2 and FGFR3 genes on chromosomes 8, 10 and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TACC3 (D-2) | sc-48368 | 200 µg/ml | $316.00 | |||
TACC3 (D-2): m-IgG Fc BP-HRP Kit | sc-536816 | 200 µg Ab; 10 µg BP | $354.00 | |||
TACC3 (D-2): m-IgGκ BP-HRP Kit | sc-533982 | 200 µg Ab; 40 µg BP | $354.00 | |||
TACC3 (D-2): m-IgG1 BP-HRP Kit | sc-544837 | 200 µg Ab; 20 µg BP | $354.00 |