Anticorps Spot 14 (D-2): sc-390953
- L'Anticorps Spot 14 (D-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 31-60 au niveau d'une région interne de Spot 14 d'origine human
- recommandé pour la détection de Spot 14 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Spot 14 Antibody (D-2) for WB applications. Ces réactifs sont désormais proposés en lots avec Spot 14 Antibody (D-2)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
Spot 14, also known as S14 or THRSP (thyroid hormone responsive protein), is a small acidic protein localizing to the nucleus and can be found in tissues that synthesize triglycerides, such as liver, mammary glands and adipose tissues. Spot 14 is implicated in growth and differentiation, possibly functioning as a transcription regulator for genes encoding proteins that participate in lipogenesis. A variety of lipogenic stimuli can activate the expression of Spot 14, including thyroid hormone, dietary carbohydrate, Insulin and glucose. Its expression can be downregulated by catecholamine and glucagon. In addition, Spot 14 expression is known to oscillate with the circadian clock. Knockdown of Spot 14 leads to impaired lipid synthesis and apoptosis. In most breast cancers, Spot 14 is overexpressed and is believed to augment cell growth and survival.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Spot 14 (D-2) | sc-390953 | 200 µg/ml | $316.00 | |||
Spot 14 (D-2): m-IgG Fc BP-HRP Kit | sc-540875 | 200 µg Ab; 10 µg BP | $354.00 | |||
Spot 14 (D-2): m-IgG1 BP-HRP Kit | sc-542433 | 200 µg Ab; 20 µg BP | $354.00 | |||
Spot 14 (D-2) peptide neutralisant | sc-390953 P | 100 µg/0.5 ml | $68.00 |