Anticorps SGTA (G-11): sc-373978
- L'Anticorps SGTA (G-11) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 41-120 situés près de la région N-terminus de SGTA d'origine human
- recommandé pour la détection de SGTA d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SGTA (G-11) pour les applications WB et IHC(P). Ces réactifs sont désormais proposés en lots avec l'anticorps SGTA (G-11)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
SGTA (small glutamine-rich tetratricopeptide repeat (TPR)-containing protein A or alpha), also known as SGT, hSGT or UBP (Vpu-binding protein), is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. SGTA is believed to function as a component of the androgen receptor (AR)-chaperone-co-chaperone complex, acting as a co-chaperone involved in androgen signaling. More specifically, SGTA binds to the hinge region of the AR functions to retain the AR in the cytoplasm, thereby inhibiting androgen signaling. In addition, SGTA functions as a co-chaperone for HSP 90 and HSP 70, two proteins known to participate in apoptosis. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. SGTA also interacts with the nonstructural Parvovirus protein NS1 and the HIV-1 proteins Vpu and Gag.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SGTA (G-11) | sc-373978 | 200 µg/ml | $316.00 | |||
SGTA (G-11): m-IgGκ BP-HRP Kit | sc-535356 | 200 µg Ab; 40 µg BP | $354.00 | |||
SGTA (G-11): m-IgG2b BP-HRP Kit | sc-549401 | 200 µg Ab; 10 µg BP | $354.00 |