Date published: 2025-9-9

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Anticorps PDE9A (E-2): sc-271754

5.0(2)
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Fiches techniques
  • L'Anticorps PDE9A (E-2) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 424-593 situés au niveau C-terminus de PDE9A d'origine human
  • recommandé pour la détection de PDE9A d'origine human par WB, IP, IF et ELISA
  • m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps PDE9A (E-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps PDE9A (E-2)(voir les informations de commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    Phosphodiesterases (PDEs) also designated cyclic nucleotide phosphodiesterases, are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase 9A (PDE9A) is a 593 amino acid protein that plays a role in signal transduction via regulation of the intracellular concentration of cyclic nucleotides and has a high affinity for cGMP. There are 15 known isoforms of PDE9A. It is expressed in various tissues including testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate. Highest levels of PDE9A expression occur in brain, kidney, spleen, colon, heart and colon, while there is no detection of PDE9A in blood. PDE9A is composed of an N-terminal regulatory domain and a C-terminal catalytic domain containing two possible divalent metal sites. It may be implicated in affective bipolar disorder.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps PDE9A (E-2)

    sc-271754
    200 µg/ml
    $316.00

    PDE9A (E-2): m-IgG Fc BP-HRP Kit

    sc-537691
    200 µg Ab; 10 µg BP
    $354.00

    PDE9A (E-2): m-IgGκ BP-HRP Kit

    sc-535039
    200 µg Ab; 40 µg BP
    $354.00

    PDE9A (E-2): m-IgG2a BP-HRP Kit

    sc-548087
    200 µg Ab; 10 µg BP
    $354.00

    What is the recommended fixation method for immunofluorescence staining with PDE9A (E-2): sc-271754 monoclonal antibody?

    Posée par: AbPolly
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Répondue par: Technical Support
    Date de publication: 2017-02-25
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    Rated 5 de 5 de par Produced superb immunofluorescence cytoplasmicProduced superb immunofluorescence cytoplasmic staining in formalin-fixed HepG2 cells. -SCBT QC
    Date de publication: 2015-01-30
    Rated 5 de 5 de par Great Western Blot data of PDE9A expression in nonGreat Western Blot data of PDE9A expression in non-transfected and human PDE9A transfected 293 whole cell lysates. -SCBT QC
    Date de publication: 2013-09-17
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    Anticorps PDE9A (E-2) est évalué 5.0 de 5 de 2.
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