Date published: 2025-12-6

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PDE5A Antibodies

Santa Cruz Biotechnology delivers a wide array of PDE5A monoclonal antibodies for investigating phosphodiesterase 5A in various biological processes. PDE5A monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Phosphodiesterase 5A regulates intracellular levels of cyclic guanosine monophosphate (cGMP), playing a crucial role in vascular smooth muscle relaxation and blood flow regulation. PDE5A has emerged as a significant focus in cardiovascular research due to its involvement in various cardiovascular diseases and erectile dysfunction. Research into PDE5A continues to reveal new insights about its regulatory mechanisms and potential therapeutic applications. Understanding phosphodiesterase 5A function has become increasingly important for developing targeted treatments and improving clinical outcomes. Ongoing studies of PDE5A contribute to advancing our knowledge of cellular signaling pathways and their impact on human health. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of phosphodiesterase 5A and its role in human health and disease.

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PDE5A Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PDE5A Antibody (D-3)

sc-398747mouse IgG1 κ31-150 (h)WB, IP, IF, ELISAm, r, h
3
(4)

PDE5A Antibody (54)

sc-136027mouse IgG12-108 (r)WB, IPm, r
1
(1)

PDE5A CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDE5A CRISPR/Cas9 KO Plasmid (h)

sc-401627hGene KnockoutGFP0
(0)

PDE5A HDR Plasmid (h)

sc-401627-HDRhHomology Directed RepairPuromycin0
(0)

PDE5A Double Nickase Plasmid (h)

sc-401627-NIChGene KnockoutPuromycin0
(0)

PDE5A Double Nickase Plasmid (h2)

sc-401627-NIC-2hGene KnockoutPuromycin0
(0)

PDE5A CRISPR/Cas9 KO Plasmid (m)

sc-433880mGene KnockoutGFP0
(0)

PDE5A HDR Plasmid (m)

sc-433880-HDRmHomology Directed RepairPuromycin0
(0)

PDE5A Double Nickase Plasmid (m)

sc-433880-NICmGene KnockoutPuromycin0
(0)

PDE5A Double Nickase Plasmid (m2)

sc-433880-NIC-2mGene KnockoutPuromycin0
(0)

PDE5A CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDE5A CRISPR Activation Plasmid (h)

sc-401627-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDE5A CRISPR Activation Plasmid (h2)

sc-401627-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDE5A Lentiviral Activation Particles (h)

sc-401627-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDE5A Lentiviral Activation Particles (h2)

sc-401627-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PDE5A CRISPR Activation Plasmid (m)

sc-433880-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDE5A CRISPR Activation Plasmid (m2)

sc-433880-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PDE5A Lentiviral Activation Particles (m)

sc-433880-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDE5A Lentiviral Activation Particles (m2)

sc-433880-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PDE5A siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDE5A siRNA (h)

sc-44918hGene SilencingN/A
1
(0)

PDE5A shRNA Plasmid (h)

sc-44918-SHhGene SilencingPuromycin
1
(0)

PDE5A shRNA (h) Lentiviral Particles

sc-44918-VhGene SilencingPuromycin
1
(0)

PDE5A siRNA (m)

sc-44919mGene SilencingN/A0
(0)

PDE5A shRNA Plasmid (m)

sc-44919-SHmGene SilencingPuromycin0
(0)

PDE5A shRNA (m) Lentiviral Particles

sc-44919-VmGene SilencingPuromycin0
(0)