Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+). Excluding NHE-1, which is ubiquitously expressed, NHE isoforms-2-6 have distinct tissue- and cell type- dependent expression, and inhibitiory characteristics by amiloride analogs. Mammalian NHE-3 protein, also known as solute carrier family 9 isoform-3 or SLC9A3, is a major absorptive NHE in kidney and intestine that influences ion homeostasis by mediating sodium absorption.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps p-NHE-3 (10A8) | sc-53961 | 200 µg/ml | $316.00 | |||
p-NHE-3 (10A8): m-IgGκ BP-HRP Kit | sc-534202 | 200 µg Ab; 40 µg BP | $354.00 |