NHE Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-(N-Ethyl-N-isopropyl)-Amiloride | 1154-25-2 | sc-202458 | 5 mg | $102.00 | 20 | |
5-(N-Ethyl-N-isopropyl)-Amiloride is a potent inhibitor of the sodium-hydrogen exchanger (NHE), characterized by its ability to selectively disrupt ion transport mechanisms. Its unique molecular structure allows for specific interactions with the exchanger's binding sites, leading to altered ion gradients across membranes. This compound exhibits distinct reaction kinetics, with a rapid onset of action that influences cellular pH regulation and ion homeostasis, showcasing its role in modulating cellular environments. | ||||||
Amiloride, 5-(N,N-Dimethyl)-, hydrochloride | 2235-97-4 | sc-202459 | 5 mg | $230.00 | 7 | |
5-(N,N-Dimethyl)-Amiloride hydrochloride is a selective antagonist of the sodium-hydrogen exchanger (NHE), distinguished by its unique ability to modulate ion transport dynamics. Its molecular configuration facilitates strong binding interactions with the exchanger, effectively altering intracellular sodium and hydrogen ion concentrations. This compound demonstrates notable reaction kinetics, exhibiting a swift inhibitory effect that impacts cellular ionic balance and pH stability, highlighting its role in cellular ion regulation. | ||||||
KR-32568 | 852146-73-7 | sc-252934 | 5 mg | $160.00 | ||
KR-32568 functions as a potent inhibitor of the sodium-hydrogen exchanger (NHE), characterized by its unique structural features that enhance binding affinity to the exchanger's active site. This compound exhibits distinct molecular interactions, promoting conformational changes that disrupt ion transport pathways. Its kinetic profile reveals rapid onset of action, significantly influencing cellular ion homeostasis and contributing to the modulation of pH levels within the cellular environment. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $56.00 | 6 | |
Amiloride • HCl acts as a selective modulator of the sodium-hydrogen exchanger (NHE), showcasing unique binding dynamics that stabilize the exchanger's conformation. This compound engages in specific electrostatic interactions, facilitating a nuanced alteration in ion transport mechanisms. Its reaction kinetics indicate a pronounced effect on ion flux, thereby influencing intracellular sodium and hydrogen ion concentrations, which can lead to significant shifts in cellular pH regulation. | ||||||
5-(N-Methyl-N-isobutyl)-Amiloride | 96861-65-3 | sc-202929 sc-202929A | 5 mg 25 mg | $82.00 $189.00 | ||
5-(N-Methyl-N-isobutyl)-Amiloride functions as a potent inhibitor of the sodium-hydrogen exchanger (NHE), exhibiting distinctive molecular interactions that disrupt ion exchange processes. Its structural features allow for targeted binding, which alters the conformational state of the exchanger. This compound influences the kinetics of ion transport, resulting in modified intracellular sodium and hydrogen ion levels, thereby impacting cellular homeostasis and pH balance. | ||||||