Date published: 2026-1-8

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NHE-8 Antibodies

Santa Cruz Biotechnology offers a broad range of NHE-8 monoclonal antibodies for research focused on understanding sodium/hydrogen exchanger 8 (NHE-8) protein function. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). NHE-8 is a vital protein involved in the regulation of intracellular pH and sodium homeostasis, playing a crucial role in cellular function and signaling. Its importance extends to various physiological processes, including renal function and the maintenance of electrolyte balance. Dysregulation of NHE-8 has been implicated in several pathophysiological conditions, making it a significant target for research. Researchers can utilize NHE-8 monoclonal antibodies to investigate cellular pH regulation mechanisms and sodium transport pathways. Understanding NHE-8 function and regulation provides valuable insights into disorders affecting pH homeostasis and sodium balance. Current research highlights the significance of NHE-8 in maintaining cellular health and its potential therapeutic implications. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of NHE-8's role in health and disease.

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NHE-8 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

NHE-8 Antibody (7A11)

sc-53902mouse IgG1 κ492-581 (h)WB, IP, IF, IHC(P)m, r, h

new

(2)

NHE-8 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NHE-8 CRISPR/Cas9 KO Plasmid (h)

sc-417946hGene KnockoutGFP0
(0)

NHE-8 HDR Plasmid (h)

sc-417946-HDRhHomology Directed RepairPuromycin0
(0)

NHE-8 Double Nickase Plasmid (h)

sc-417946-NIChGene KnockoutPuromycin0
(0)

NHE-8 Double Nickase Plasmid (h2)

sc-417946-NIC-2hGene KnockoutPuromycin0
(0)

NHE-8 CRISPR/Cas9 KO Plasmid (m)

sc-429483mGene KnockoutGFP0
(0)

NHE-8 HDR Plasmid (m)

sc-429483-HDRmHomology Directed RepairPuromycin0
(0)

NHE-8 Double Nickase Plasmid (m)

sc-429483-NICmGene KnockoutPuromycin0
(0)

NHE-8 Double Nickase Plasmid (m2)

sc-429483-NIC-2mGene KnockoutPuromycin0
(0)

NHE-8 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NHE-8 CRISPR Activation Plasmid (h)

sc-417946-ACThGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 CRISPR Activation Plasmid (h2)

sc-417946-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 Lentiviral Activation Particles (h)

sc-417946-LAChGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 Lentiviral Activation Particles (h2)

sc-417946-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 CRISPR Activation Plasmid (m)

sc-429483-ACTmGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 CRISPR Activation Plasmid (m2)

sc-429483-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 Lentiviral Activation Particles (m)

sc-429483-LACmGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 Lentiviral Activation Particles (m2)

sc-429483-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

NHE-8 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

NHE-8 siRNA (h)

sc-75912hGene SilencingN/A0
(0)

NHE-8 shRNA Plasmid (h)

sc-75912-SHhGene SilencingPuromycin0
(0)

NHE-8 shRNA (h) Lentiviral Particles

sc-75912-VhGene SilencingPuromycin0
(0)

NHE-8 siRNA (m)

sc-149957mGene SilencingN/A0
(0)

NHE-8 shRNA Plasmid (m)

sc-149957-SHmGene SilencingPuromycin0
(0)

NHE-8 shRNA (m) Lentiviral Particles

sc-149957-VmGene SilencingPuromycin0
(0)