Anticorps ORC6 (D-4): sc-390490
- L'Anticorps ORC6 (D-4) est un monoclonal de souris IgG1 κ, cité dans 2 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 1-252 correspondant à la séquence totale de ORC6 d'origine human
- recommandé pour la détection de ORC6 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour ORC6 Antibody (D-4) for WB applications. Ces réactifs sont désormais proposés en lots avec ORC6 Antibody (D-4)(voir les informations de commande ci-dessous).
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation. Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins. ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ORC6 (D-4) | sc-390490 | 200 µg/ml | $316.00 | |||
ORC6 (D-4): m-IgG Fc BP-HRP Kit | sc-540806 | 200 µg Ab; 10 µg BP | $354.00 | |||
ORC6 (D-4): m-IgG1 BP-HRP Kit | sc-542381 | 200 µg Ab; 20 µg BP | $354.00 |