Anticorps ORC4 (D-8): sc-393985
- L'anticorps ORC4 D-8 est un monoclonal IgM (chaîne légère kappa) L'Anticorps ORC4 fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 375-398 près de C-terminus de ORC4 d'origine human
- recommandé pour la détection de ORC4 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-393985 X, 200 µg/0.1 ml)
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire ORC4 (D-8). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ORC4 Antibody (D-8) is an IgM κ mouse monoclonal ORC4 antibody (also designated ORC4 antibody) that detects the ORC4 protein of mouse, rat and human origin by WB, IP, IF and ELISA. ORC4 Antibody (D-8) is available as the non-conjugated anti-ORC4 antibody. The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation. Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins, which bind specifically to origins of replication, where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests ORC proteins play a crucial role in the G1/S transition in mammalian cells.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ORC4 (D-8) | sc-393985 | 200 µg/ml | $316.00 | |||
ORC4 (D-8) peptide neutralisant | sc-393985 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps ORC4 (D-8) X | sc-393985 X | 200 µg/0.1 ml | $316.00 |