Anticorps NKG2 (6A447): sc-71706
- L'anticorps NKG2 6A447 est un monoclonal IgG2a de rat fourni en 200 µg/ml
- dirigé contre NKG2 d'origine mouse
- recommandé pour la détection de NKG2-A, NKG2-C and NKG2-E d'originie mouse par FCM
- disponible conjugué soit à la phycoérythrine soit à la FITC pour IF, IHC(P) et FCM
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire NKG2 (6A447). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired Immuno-globulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ ab T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NKG2 (6A447) | sc-71706 | 200 µg/ml | $316.00 | |||
Anticorps NKG2 (6A447) FITC | sc-71706 FITC | 200 µg/ml | $330.00 | |||
Anticorps NKG2 (6A447) PE | sc-71706 PE | 200 µg/ml | $343.00 |