Anticorps ITM1 (JA-07): sc-100796
- L'Anticorps ITM1 (JA-07) est un monoclonal de souris IgG1 κ, cité dans 4 publications, fourni en 100 µg/ml
- dirigé contre la ITM1 recombinante d'origine human
- recommandé pour la détection de ITM1 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire ITM1 (JA-07). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
ITM1 (integral membrane protein 1), also known as TMC (transmembrane protein TMC) or STT3A (STT3, subunit of the oligosaccharyltransferase complex, homolog A), is a member of the STT3 family of proteins. Predominantly expressed in liver, pancreas, muscle, placenta and skin fibroblasts, ITM1 is a multi-pass membrane protein that localizes to the membrane of the endoplasmic reticulum (ER). ITM1 is one of two multicellular eukaryotic homologs of the S. cerevisiae protein Stt3, an essential component of the yeast OST (oligosaccharyltransferase) complex. Both homologs (ITM1 and SIMP) are glycosylated and function as the catalytic component of the mammalian OST complex which is responsible for catalyzing the transfer of a high mannose oligosaccharide to an asparagine residue in nascent proteins that enter the lumen of the ER. Using lipid-linked oligosaccharides as donors, the OST complex specifically transfers the oligosaccharide to the asparagine residue in an Asn-X-Ser/Thr consensus motif (X is any amino acid excluding proline). Compared with SIMP, ITM1 is less active but also more selective in terms of substrates.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps ITM1 (JA-07) | sc-100796 | 100 µg/ml | $333.00 |