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Human immunodeficiency virus (HIV) is a retrovirus that causes acquired im-mune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. p17 is a structural matrix protein of HIV-1 that enters the nucleus rapidly after viral synthesis. HIV-1 Rev is an RNA-binding, trans-activator protein that is readily phosphorylated at separate regions by protein kinase CK2 and MAP kinase. Rev plays a role in viral replication, and it specifically induces the accumulation in the cytoplasm of intron-containing mRNAs normally kept in the nucleus.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HIV-1 Rev (Rev-6) | sc-69730 | 200 µg/ml | $316.00 | |||
HIV-1 Rev (Rev-6): m-IgG Fc BP-HRP Kit | sc-539232 | 200 µg Ab; 10 µg BP | $354.00 | |||
HIV-1 Rev (Rev-6): m-IgG1 BP-HRP Kit | sc-541341 | 200 µg Ab; 20 µg BP | $354.00 |