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Rho, the Ras-related small GTPase, is responsible for the regulation of actin-based cytoskeletal structures including stress fibers, focal adhesions, and the contractile ring apparatus. CRIK (Citron Rho-interacting kinase), also known as CIT, citron or STK21, is a 2,027 amino acid cytoplasmic protein that belongs to the protein kinase superfamily and the AGC Ser/Thr protein kinase family. Containing an AGC-kinase C-terminal domain, a CNH domain, a PH domain, a phorbol-ester/DAG-type zinc finger and a protein kinase domain, CRIK is suggested to play a role in the regulation of cytokinesis and the development of the central nervous system. CRIK is required for KIF14 localization to the central spindle and midbody. CRIK exists as four alternatively spliced isoforms and is encoded by a gene located on chromosome 12q24.23.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CRIK (C-5) | sc-377449 | 200 µg/ml | $316.00 | |||
CRIK (C-5): m-IgG Fc BP-HRP Kit | sc-540719 | 200 µg Ab; 10 µg BP | $354.00 | |||
CRIK (C-5): m-IgG1 BP-HRP Kit | sc-542321 | 200 µg Ab; 20 µg BP | $354.00 | |||
CRIK (C-5) peptide neutralisant | sc-377449 P | 100 µg/0.5 ml | $68.00 |