Anticorps CLK3 (4F12): sc-134301
- L'Anticorps CLK3 (4F12) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 100 µg/ml
- élevé contre la protéine recombinante CLK3 d'origine human.
- recommandé pour la détection de CLK3 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire CLK3 (4F12). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. CLK3 (CDC-like kinase 3), also known as PHCLK3, is a 638 amino acid nuclear and cytoplasmic protein that belongs to the Ser/Thr protein kinase family. Functioning as a dual-specificity kinase, CLK3 catalyzes the ATP-dependent phosphorylation of argine- and serine-rich (SR) splicing factor proteins, thereby regulating both their function and their intranuclear distribution. Via its enzymatic activity, CLK3 is thought to be one of several members of a network of regulatory proteins that control RNA splicing events. Four isoforms of CLK3 exist due to alternative splicing.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CLK3 (4F12) | sc-134301 | 100 µg/ml | $333.00 |