Anti-L'anticorps Atg16 E-10 est un monoclonal IgG1 κ L'Anticorps Atg16, cité dans 7 publications, fourni en 200 µg/ml
dirigé contre les acides aminés 15-70 situés près de la région N-terminus de Atg16 d'origine human
Anti-L'Anticorps Atg16 (E-10) est recommandé pour la détection de Atg16 d'origine mouse, rat et human par WB, IP, IF et ELISA
Anti-L'Anticorps Atg16 (E-10) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
Contactez notre Service Technique (ou votre Distributeur local) pour plus d'informations pour recevoir un échantillon GRATUIT de 10 µg de Atg16 (E-10): sc-393274.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Atg16 Antibody (E-10) for WB applications. This reagent is now offered in a bundle with Atg16 Antibody (E-10) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Atg16 Antibody (E-10) is a high quality monoclonal Atg16 antibody (also designated Atg16 antibody) suitable for the detection of the Atg16 protein of mouse, rat and human origin. Atg16 Antibody (E-10) is available as both the non-conjugated anti-Atg16 antibody form, as well as multiple conjugated forms of anti-Atg16 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Atg16, also known as ATG16L1, IBD10 or WDR30, is a 607 amino acid protein that localizes to both the cytoplasm and the peripheral membrane and contains 7 WD-repeats. Existing as a homooligomer, Atg16 interacts with APG5 and plays a crucial role in autophagy, the major intracellular degradation system that delivers cytoplasmic proteins to lysosomes for destruction. Genetic variations in the gene encoding Atg16 are associated with susceptibility to inflammatory bowel disease type 10 (IBD10), a chronic relapsing intestinal inflammation. Multiple isoforms of Atg16 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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