TMEM245 activators, as hypothesized in this context, represent a diverse group of chemical compounds that indirectly influence the activity or expression of the TMEM245 protein through a variety of mechanisms. These activators target different aspects of cellular function, from the modulation of cAMP levels and activation of specific receptors that influence gene expression, to the alteration of cellular stress responses and metabolic signaling pathways. This indirect activation approach recognizes the complex regulation of transmembrane proteins and leverages the interconnected nature of cellular signaling pathways to influence the expression or function of TMEM245.
For instance, compounds like forskolin and resveratrol act by elevating intracellular signaling molecules or activating specific sirtuins, respectively, which can lead to changes in the cellular environment conducive to the expression or activity of TMEM245. Similarly, agents such as vitamin D3 and retinoic acid work through their respective receptors to directly modulate gene expression, potentially leading to an increase in TMEM245 levels. The role of dietary components and supplements, such as omega-3 fatty acids and zinc, underscores the potential for nutritional and environmental factors to influence gene expression and protein activity within the cell.
This speculative list illustrates the potential avenues through which the activity or expression of TMEM245 might be enhanced, reflecting a nuanced understanding of cellular biology and the multifaceted roles that proteins play within complex cellular networks. By focusing on the broader cellular context and the myriad ways in which chemical compounds can influence gene expression and signaling pathways, this approach highlights the potential for targeting upstream regulatory mechanisms or related cellular processes to modulate the function of proteins like TMEM245 indirectly.
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Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Augmente les niveaux d'AMPc, renforçant potentiellement l'expression du TMEM245 par des voies dépendantes de l'AMPc. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influence l'expression des gènes par l'intermédiaire des récepteurs de l'acide rétinoïque, en régulant potentiellement le TMEM245. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Modifie les voies de signalisation, augmentant probablement l'expression du TMEM245 en affectant la régulation des gènes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Affecte la signalisation NF-κB, conduisant potentiellement à la modulation de l'expression de TMEM245. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Active SIRT1, influençant les voies qui pourraient renforcer l'expression du TMEM245 en réponse au stress cellulaire. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Active le récepteur de la vitamine D, affectant potentiellement l'expression du TMEM245 par le biais de la régulation génomique. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Induit la signalisation NRF2, renforçant probablement l'expression de TMEM245 en modulant la réponse au stress oxydatif. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Active l'AMPK, influençant potentiellement les voies de signalisation métaboliques qui régulent le TMEM245. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Inhibiteur d'histone-désacétylase qui peut augmenter l'expression du TMEM245 en modifiant l'accessibilité de la chromatine. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essentiel pour la synthèse de l'ADN et la régulation de la transcription, ce qui pourrait favoriser l'expression du TMEM245. |