Assuming "LIN-35" refers to a protein or gene that is integral to a particular biological process, activators of LIN-35 would be molecules that enhance its biological activity. These activators could potentially work by binding directly to the LIN-35 protein, inducing a conformational change that results in increased activity, or by facilitating its interaction with other proteins or substrates. The chemical structures of LIN-35 activators would likely be diverse, as they would need to possess specific characteristics that enable them to interact with distinct structural motifs or domains within LIN-35. These characteristics could include particular arrangements of atoms, charged groups, hydrophobic or hydrophilic elements, or even larger molecular frameworks for protein-protein interaction modulation.
In the realm of research, scientists investigating LIN-35 activators would employ a variety of techniques to understand the interaction between these molecules and the LIN-35 protein. Studies might include computational modeling to predict how these activators could bind to the protein and what effects they may exert on its structure and function. Experimental approaches would likely involve the use of in vitro assays to assess the biochemical consequences of activator binding, such as changes in the enzymatic activity of LIN-35 or alterations in its ability to interact with other cellular components. Advanced analytical techniques like mass spectrometry, circular dichroism, and fluorescence spectroscopy could provide insights into the binding dynamics and structural changes. Furthermore, if the precise structure of the LIN-35 protein were known, techniques such as X-ray crystallography or cryo-electron microscopy might be used to solve the structure of the protein in complex with activator molecules, giving a clear picture of the molecular interactions at play. This could elucidate the mechanism by which these activators enhance LIN-35 activity. Nonetheless, without concrete scientific evidence to define "LIN-35 Activators," this discussion remains purely theoretical and is not grounded in any known chemical classification.
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Nom du produit | CAS # | Ref. Catalogue | Quantité | Prix HT | CITATIONS | Classement |
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Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
L'hydroxyurée induit des lésions de l'ADN et peut affecter les protéines régulatrices du cycle cellulaire, modifiant potentiellement l'expression de LIN-35 dans le cadre d'une réponse au stress. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
La camptothécine induit des lésions de l'ADN en inhibant la topoisomérase I, ce qui pourrait entraîner des modifications de l'expression de LIN-35 en tant que réponse cellulaire. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
L'étoposide provoque des cassures de brins d'ADN via l'inhibition de la topoisomérase II, ce qui pourrait influencer l'expression de LIN-35 pendant la réponse aux lésions de l'ADN. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
La roscovitine est un inhibiteur de la kinase cycline-dépendante et peut avoir un impact sur les régulateurs du cycle cellulaire, y compris potentiellement le LIN-35. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
L'aphidicoline est un inhibiteur de l'ADN polymérase, ce qui peut entraîner des modifications de l'expression de LIN-35 dans le cadre de l'activation du point de contrôle du cycle cellulaire. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Le paclitaxel stabilise les microtubules et arrête les cellules en mitose, affectant potentiellement l'expression de LIN-35 dans le processus. | ||||||
Thymidine | 50-89-5 | sc-296542 sc-296542A sc-296542C sc-296542D sc-296542E sc-296542B | 1 g 5 g 100 g 250 g 1 kg 25 g | $48.00 $72.00 $265.00 $449.00 $1724.00 $112.00 | 16 | |
La thymidine peut entraîner un blocage du cycle cellulaire en phase S lorsqu'elle est utilisée à des concentrations élevées, ce qui peut influencer l'expression de LIN-35. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
Le méthotrexate inhibe la dihydrofolate réductase, entraînant un arrêt de la phase S, ce qui pourrait avoir un impact sur l'expression des régulateurs du cycle cellulaire tels que LIN-35. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Le nocodazole perturbe la polymérisation des microtubules, entraînant l'arrêt du cycle cellulaire, ce qui pourrait affecter les niveaux d'expression de LIN-35. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Le cisplatine forme des adduits à l'ADN, entraînant l'activation de la réponse aux lésions de l'ADN, ce qui peut influencer l'expression de LIN-35 dans le cadre de la réponse cellulaire. |