Anti-Ref-1 Anticuerpo C-4 es un monoclonal de ratón IgG2b κ Ref-1 Anticuerpo, ver las 48 publicaciones, proporcionado como 200 µg/ml
producido contra los amino ácidos 1-300 de Ref-1 de origen human
Ref-1 Anticuerpo (C-4) es recomendado para detectar Ref-1 de mouse, rat y human origen, mediante WB, IP, IF y IHC(P)
Ref-1 Anticuerpo (C-4) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
TransCruz reactivo para Gel Supershift y ChIP (sc-17774 X, 200 µg/0.1 ml)
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Ref-1 (C-4): sc-17774.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Ref-1 Antibody (C-4) for WB and IHC(P) applications. This reagent is now offered in a bundle with Ref-1 Antibody (C-4) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Ref-1 para análisis funcionales de las repuestas celulares a Ref-1
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Ref-1 Antibody (C-4) is a high quality monoclonal Ref-1 antibody (also designated apurinic/apyrimidinic (AP) endodeoxyribonuclease 1 antibody, APE1 antibody, apurinic/apyrimidinic (AP) activity DNA repair enzyme antibody, AP endonuclease (APEN) antibody, or DNA-(apurinic or apyrimidinic site) lyase antibody) suitable for the detection of the Ref-1 protein of mouse, rat and human origin. Ref-1 Antibody (C-4) is available as both the non-conjugated anti-Ref-1 antibody form, as well as multiple conjugated forms of anti-Ref-1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The role of transcription factors in the regulation of gene expression is well established. Although the activity of these factors can be regulated by phosphorylation, evidence has indicated regulation of DNA binding mediated by changes in reduction-oxidation (redox) status. Mutational analysis has identified a single conserved cysteine residue mapping within the DNA binding domains of Fos and Jun. Chemical oxidation or modification of this cysteine residue inhibits the DNA binding activity of Fos and Jun. A similar mode of regulation has been recently proposed for other nuclear transcription factors. Oxidation is reversible by these compounds or by a cellular redox/DNA repair protein identified originally as Ref-1 (redox factor 1). Ref-1 is identical to a previously characterized DNA repair enzyme designated HAP1, APE or APEX.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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