The term KIAA1822L Activators suggests a class of chemical compounds postulated to interact with a protein encoded by a gene that might be designated as KIAA1822L. The KIAA nomenclature originates from a series of genes identified by the Kazusa DNA Research Institute, where many of these genes were initially cataloged without detailed functional information. The protein KIAA1822L would, therefore, require initial investigative research to determine its cellular role, expression patterns, and biochemical properties. If KIAA1822L activators existed, they would be molecules designed to enhance the activity of this protein, which would involve increasing its expression, activity, stability, or modulating its interactions with other cellular components. The design and discovery process of such activators would likely be initiated by high-throughput chemical screening, aiming to identify compounds that can positively modulate the protein's function. Subsequent validation steps would include verifying the specificity of these activators to ensure that the observed effects are due to direct interaction with the KIAA1822L protein.
Developing a deeper understanding of the interaction between KIAA1822L activators and their target protein would involve a series of advanced analytical techniques. Researchers might employ methods such as affinity chromatography to quantify the binding affinity of the activators, or use mass spectrometry to elucidate the molecular weight and structural features of the protein-activator complexes. Additionally, computational tools like molecular dynamics simulations could predict how the activators affect the protein's structure and function. Nuclear magnetic resonance (NMR) spectroscopy could provide insights into the conformational changes within the protein upon activator binding. Through these methods, scientists would seek to map the activator binding sites, understand the mechanism of activation, and characterize the molecular interactions at play. This detailed molecular characterization would be essential for researchers to fully grasp the biochemical implications of activating the KIAA1822L protein, even though, as of now, such a protein and its corresponding activators are purely speculative and not grounded in the current scientific literature.
Items 1 to 10 of 12 total
Mostrar:
| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
La metformina activa la AMPK y puede influir en las vías metabólicas, aumentando potencialmente la expresión de IDH para satisfacer las demandas energéticas alteradas. | ||||||
Phenformin Hydrochloride | 834-28-6 | sc-219590 | 10 g | $119.00 | 4 | |
La fenformina es otra biguanida que activa la AMPK. También puede afectar a la expresión de IDH como parte de su impacto en el metabolismo. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
La berberina activa la AMPK, influyendo en las vías metabólicas. Hipotéticamente, podría aumentar la expresión de IDH debido a cambios metabólicos. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
La nicotinamida es una forma de vitamina B3 y un precursor de NAD+, que podría afectar indirectamente a la expresión de IDH a través del equilibrio NAD+/NADP+. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
El resveratrol influye en la actividad de la sirtuina y las vías AMPK, lo que podría influir en la expresión de IDH como parte de su efecto sobre el metabolismo. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
El ácido α-lipoico interviene en la bioenergética mitocondrial y puede afectar a la expresión de IDH debido a su papel en el metabolismo energético. | ||||||
Sodium dichloroacetate | 2156-56-1 | sc-203275 sc-203275A | 10 g 50 g | $55.00 $209.00 | 6 | |
El dicloroacetato afecta a la actividad de la piruvato deshidrogenasa y puede alterar la expresión de IDH a medida que la célula ajusta sus vías metabólicas. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Como análogo de la glucosa, inhibe la glucólisis y podría conducir indirectamente a la regulación al alza de la expresión de IDH para compensar la producción de energía. | ||||||
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $41.00 $96.00 | ||
El piruvato es un metabolito clave en las vías energéticas celulares y teóricamente podría modular la expresión de IDH como parte de la red metabólica. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $306.00 $963.00 $7980.00 | 1 | |
El oxaloacetato es un componente del ciclo del ácido cítrico y podría potencialmente señalar cambios que influyan en la expresión de IDH. | ||||||