Date published: 2025-9-11

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IDHC Activators

The term KIAA1822L Activators suggests a class of chemical compounds postulated to interact with a protein encoded by a gene that might be designated as KIAA1822L. The KIAA nomenclature originates from a series of genes identified by the Kazusa DNA Research Institute, where many of these genes were initially cataloged without detailed functional information. The protein KIAA1822L would, therefore, require initial investigative research to determine its cellular role, expression patterns, and biochemical properties. If KIAA1822L activators existed, they would be molecules designed to enhance the activity of this protein, which would involve increasing its expression, activity, stability, or modulating its interactions with other cellular components. The design and discovery process of such activators would likely be initiated by high-throughput chemical screening, aiming to identify compounds that can positively modulate the protein's function. Subsequent validation steps would include verifying the specificity of these activators to ensure that the observed effects are due to direct interaction with the KIAA1822L protein.

Developing a deeper understanding of the interaction between KIAA1822L activators and their target protein would involve a series of advanced analytical techniques. Researchers might employ methods such as affinity chromatography to quantify the binding affinity of the activators, or use mass spectrometry to elucidate the molecular weight and structural features of the protein-activator complexes. Additionally, computational tools like molecular dynamics simulations could predict how the activators affect the protein's structure and function. Nuclear magnetic resonance (NMR) spectroscopy could provide insights into the conformational changes within the protein upon activator binding. Through these methods, scientists would seek to map the activator binding sites, understand the mechanism of activation, and characterize the molecular interactions at play. This detailed molecular characterization would be essential for researchers to fully grasp the biochemical implications of activating the KIAA1822L protein, even though, as of now, such a protein and its corresponding activators are purely speculative and not grounded in the current scientific literature.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
1 g
5 g
10 g
50 g
100 g
250 g
$30.00
$42.00
$62.00
$153.00
$255.00
$500.00
37
(1)

Metformin activates AMPK and can influence metabolic pathways, potentially increasing IDH expression to meet altered energetic demands.

Phenformin Hydrochloride

834-28-6sc-219590
10 g
$117.00
4
(1)

Phenformin is another biguanide that activates AMPK. It may also affect IDH expression as part of its impact on metabolism.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine activates AMPK, influencing metabolic pathways. It could hypothetically upregulate IDH expression due to metabolic changes.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$43.00
$65.00
$200.00
$815.00
6
(1)

Nicotinamide is a form of vitamin B3 and a precursor to NAD+, which could indirectly affect IDH expression through NAD+/NADP+ balance.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol impacts sirtuin activity and AMPK pathways, potentially influencing IDH expression as part of its effect on metabolism.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$68.00
$120.00
$208.00
$373.00
$702.00
3
(1)

α-Lipoic Acid is involved in mitochondrial bioenergetics and may affect IDH expression due to its role in energy metabolism.

Sodium dichloroacetate

2156-56-1sc-203275
sc-203275A
10 g
50 g
$54.00
$205.00
6
(1)

Dichloroacetate affects pyruvate dehydrogenase activity and may alter IDH expression as the cell adjusts its metabolic pathways.

2-Deoxy-D-glucose

154-17-6sc-202010
sc-202010A
1 g
5 g
$65.00
$210.00
26
(2)

As a glucose analog, it inhibits glycolysis and could indirectly lead to the upregulation of IDH expression to compensate for energy production.

Pyruvic acid

127-17-3sc-208191
sc-208191A
25 g
100 g
$40.00
$94.00
(0)

Pyruvate is a key metabolite in cellular energy pathways and could theoretically modulate IDH expression as part of the metabolic network.

Oxaloacetic Acid

328-42-7sc-279934
sc-279934A
sc-279934B
25 g
100 g
1 kg
$300.00
$944.00
$7824.00
1
(0)

Oxaloacetate is a component of the citric acid cycle and could potentially signal changes that influence IDH expression.