


VPS11 Antibody (S-38) is a mouse monoclonal IgG2b antibody that detects VPS11 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). VPS11, also known as END1, PEP5, RNF108, or PP3476, is crucial for proper trafficking of endocytic and biosynthetic proteins to the vacuole, playing a significant role in cell budding processes. VPS11 is predominantly localized to endosome and lysosome membranes, vital for vesicle-mediated protein trafficking and fusion/docking reactions in late endosomes and lysosomes. VPS11 is expressed ubiquitously, with highest levels in heart tissue, and contains one clathrin repeat and one RING-type zinc finger, important for interactions and functions within cellular environments. VPS11 shares 24% amino acid identity with yeast Vsp11, highlighting evolutionary conservation and importance in cellular processes. Anti-VPS11 antibody (S-38) serves as an essential tool for researchers studying protein sorting and trafficking mechanisms, providing insights into cellular function and potential disease implications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VPS11 Antibody (S-38) | sc-100893 | 100 µg/ml | $339.00 |