IDO Antibody (E-7): sc-365086
- IDO Antibody (E-7) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids . near the N-terminus of IDO of mouse origin
- recommended for detection of IDO of mouse, rat and human origin by WB, IP, IF and ELISA
- See IDO (mIDO-48): sc-53978 for IDO antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IDO Antibody (E-7) for WB applications. These reagents are now offered in bundles with IDO Antibody (E-7) (see ordering information below).
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IDO Antibody (E-7) is a mouse monoclonal IgG1 antibody that detects indoleamine 2,3-dioxygenase (IDO) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IDO is a crucial enzyme that catalyzes the degradation of the essential amino acid L-tryptophan into N-formylkynurenine, playing a significant role in immune regulation and tolerance. By modulating the availability of tryptophan, IDO influences T cell proliferation and activity, which is vital for maintaining immune homeostasis and preventing excessive immune responses. This function is particularly important in the context of pregnancy, where IDO protects allogeneic concepti from maternal immune rejection by creating a local immunosuppressive environment. Furthermore, IDO′s activity has been implicated in various pathological conditions, including cancer, where IDO can contribute to tumor immune evasion. Anti-IDO antibody (E-7) is designed to facilitate research into these critical biological processes, enabling scientists to explore the therapeutic potential of targeting IDO in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IDO Antibody (E-7) | sc-365086 | 200 µg/ml | $322.00 | |||
IDO Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-540307 | 200 µg Ab; 10 µg BP | $361.00 | |||
IDO Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-542029 | 200 µg Ab; 20 µg BP | $361.00 | |||
IDO (E-7) Neutralizing Peptide | sc-365086 P | 100 µg/0.5 ml | $69.00 |