HSF1 Antibody (A-7): sc-393677
- HSF1 Antibody (A-7) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 504-529 at the C-terminus of HSF1 of human origin
- recommended for detection of HSF1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- TransCruz reagent for ChIP application (sc-393677 X, 200 µg/0.1 ml)
- See HSF1 (E-4): sc-17757 for HSF1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HSF1 Antibody (A-7). This work is in progress.
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HSF1 Antibody (A-7) is a mouse monoclonal IgG2b light chain antibody that detects heat shock factor 1 (HSF1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HSF1 plays a crucial role in the cellular response to stress, particularly in the regulation of heat shock proteins, which are essential for protein folding and protection against cellular damage. Anti-HSF1 antibody (A-7) helps researchers study cellular homeostasis during stressful conditions, where HSF1 prevents protein aggregation and promotes cell survival. Under normal conditions, HSF1 exists as a monomer, but upon stress, HSF1 undergoes a conformational change, forming trimers that translocate to the nucleus to activate the transcription of heat shock genes. This dynamic regulation of HSF1 is critical for the cellular stress response, making HSF1 a significant target for research in various fields, including cancer biology and neurodegenerative diseases. Anti-HSF1 antibody (A-7) serves as an invaluable tool for studying the mechanisms of stress response and the role of heat shock proteins in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSF1 Antibody (A-7) | sc-393677 | 200 µg/ml | $322.00 | |||
HSF1 (A-7) Neutralizing Peptide | sc-393677 P | 100 µg/0.5 ml | $69.00 | |||
HSF1 Antibody (A-7) X | sc-393677 X | 200 µg/0.1 ml | $322.00 |