Date published: 2026-5-15

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GGT Inhibitors

Santa Cruz Biotechnology now offers a broad range of GGT Inhibitors for use in various applications. GGT (gamma-glutamyl transferase) Inhibitors are vital tools in studying the function and regulation of the enzyme gamma-glutamyl transferase, which plays a key role in the gamma-glutamyl cycle responsible for the breakdown and resynthesis of glutathione, a crucial antioxidant in cellular defense mechanisms. By inhibiting GGT, researchers can investigate the pathways through which this enzyme contributes to maintaining cellular redox balance, regulating detoxification processes, and modulating amino acid transport. In scientific research, GGT Inhibitors are used to explore the effects of altered GGT activity on cellular homeostasis and its impact on cellular processes such as apoptosis, proliferation, and oxidative stress responses. Researchers employ GGT Inhibitors to study the interactions between GGT and other cellular enzymes, as well as to identify potential regulatory pathways and targets for further investigation. The use of GGT Inhibitors supports the development of experimental models to dissect the complex interactions involving glutathione metabolism and GGT, enhancing our understanding of cellular regulation and adaptation to oxidative stress. These inhibitors facilitate comprehensive studies of the enzyme's role in cellular physiology. View detailed information on our available GGT Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Azaserine

115-02-6sc-29063
sc-29063A
50 mg
250 mg
$312.00
$924.00
15
(3)

Azaserine acts as a GGT by forming covalent bonds with key amino acid residues in the enzyme's active site, leading to irreversible inhibition. Its structural conformation allows for precise alignment with the enzyme, disrupting normal catalytic activity. The compound's ability to mimic natural substrates enhances its binding affinity, while its unique electronic properties influence the transition state of reactions, ultimately affecting metabolic pathways and enzyme kinetics.

Acivicin

42228-92-2sc-200498B
sc-200498C
sc-200498
sc-200498D
1 mg
5 mg
10 mg
25 mg
$104.00
$416.00
$655.00
$1301.00
10
(2)

Acivicin functions as a GGT through its ability to selectively interact with the enzyme's active site, where it forms stable adducts with critical thiol groups. This interaction alters the enzyme's conformation, hindering substrate access and catalytic efficiency. The compound's unique stereochemistry facilitates specific molecular recognition, while its electrophilic nature promotes rapid reaction kinetics, significantly impacting enzyme dynamics and metabolic regulation.