Zinc finger protein 391" (ZNF391) is a member of the zinc finger protein family, which is characterized by the presence of zinc finger domains-a type of protein structural motif that coordinates zinc ions to stabilize its fold. These motifs are often involved in interactions with DNA, RNA, or other proteins, and they are crucial for a variety of cellular functions, including gene expression, DNA recognition, transcriptional regulation, and signal transduction.ZNF391, like other zinc finger proteins, is presumed to function as a transcription factor, binding to specific DNA sequences to regulate the expression of target genes. The specific DNA-binding activity of ZNF391 is facilitated by its finger-like projections, which enable it to make contact with the major grooves of DNA, influencing the transcriptional machinery of the cell. By acting as a transcriptional regulator, ZNF391 can modulate various biological processes such as cell growth, differentiation, and apoptosis.
The exact physiological role and the spectrum of target genes of ZNF391 are not fully elucidated and remain an area of ongoing research. However, the importance of zinc finger proteins in development and disease processes is well-documented, suggesting that ZNF391 likely plays a significant, albeit currently unclear, role in cellular homeostasis and organismal development.The study of ZNF391 and related zinc finger proteins continues to be a significant focus within molecular biology due to their potential implications in understanding genetic regulation and their potential involvement in various pathologies, including cancer and genetic disorders. By deciphering the specific mechanisms by which ZNF391 influences gene expression, researchers hope to contribute to the broader knowledge of gene regulatory networks and their impact on health and disease.
VEJA TAMBÉM
Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
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Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
A actinomicina D inibe a síntese de ARN, afectando potencialmente a expressão de ZNF391 a nível transcricional. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
A triptolida inibe a RNA polimerase e o NF-κB, afectando potencialmente a transcrição do ZNF391 e as suas vias reguladoras. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
O flavopiridol inibe as cinases dependentes da ciclina, afectando potencialmente a regulação transcricional da ZNF391 e as suas vias associadas. | ||||||
Triamcinolone acetonide | 76-25-5 | sc-205872 sc-205872A | 50 mg 250 mg | $56.00 $149.00 | ||
O acetonido de triamcinolona é um agonista dos receptores de glucocorticóides e a sua modulação da atividade transcricional pode ter impacto na expressão de ZNF391. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A α-Amanitina inibe a RNA polimerase II, afectando potencialmente a transcrição do ZNF391 e dos seus alvos a jusante. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A tricostatina A é um inibidor da histona desacetilase, com potencial impacto na regulação epigenética da expressão de ZNF391. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
A elipticina é um agente intercalante de ADN, com potencial impacto na regulação transcricional do ZNF391 e das suas vias associadas. |