ZFR2 Activators
Zinc Chloride directly contributes to the structural integrity of ZFR2, enhancing its RNA-binding capability and thus increasing its regulatory function in RNA processing and gene expression. RG108 and 5-Azacytidine can alter DNA methylation patterns, thereby impacting the transcription of genes where ZFR2 is involved. Additionally, the inhibition of Sp1 transcription factor by Mithramycin A could influence gene expression patterns related to ZFR2's RNA binding and regulatory activities.
Compounds like Genistein, JQ1, PD98059, and LY294002, through their respective actions on tyrosine kinase signaling, BET bromodomain inhibition, MAPK/ERK pathway modulation, and PI3K/Akt pathway interference, can indirectly impact the cellular context in which ZFR2 operates. This includes its involvement in processes like signal transduction, RNA processing, and chromatin remodeling. Moreover, Trichostatin A, by influencing chromatin structure, can affect gene expression patterns, thereby impacting ZFR2's regulatory roles in RNA processing. Bortezomib and Curcumin, by modulating proteasome activity and multiple signaling pathways, respectively, might indirectly influence ZFR2's role in cellular stress responses and inflammation.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc is essential for the structural integrity of zinc finger proteins. Zinc chloride can enhance the RNA binding affinity of ZFR2, thereby potentially increasing its functional activity in RNA regulation. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor. It can alter DNA methylation patterns, which might impact the transcription of genes regulated by ZFR2. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Another DNA methyltransferase inhibitor. It can influence DNA methylation patterns, potentially affecting the transcriptional regulation of genes where ZFR2 is involved. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
An inhibitor of Sp1 transcription factor. By modulating Sp1 activity, it could influence gene expression patterns where ZFR2 is implicated in RNA binding and regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor. By altering tyrosine kinase signaling, Genistein might influence the cellular context in which ZFR2 operates, particularly in signal transduction. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
A BET bromodomain inhibitor. It may alter the expression of genes regulated by ZFR2 by influencing chromatin remodeling and transcription factor recruitment. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An ERK inhibitor. By modulating the MAPK/ERK pathway, this could impact ZFR2's role in cellular signaling and transcription regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor. By influencing the PI3K/Akt pathway, it could indirectly affect ZFR2's function in processes like RNA processing and cell survival. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor. By altering chromatin structure, it can influence gene expression patterns, potentially affecting the regulatory roles of ZFR2 in RNA processing. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor. It may indirectly influence ZFR2 activity by altering protein degradation pathways and cellular stress responses. | ||||||