YMER Activators
YMER activators are a diverse set of chemical compounds that enhance or influence the functional activity of YMER (CCDC50), a protein involved in endocytic trafficking and signal transduction. The first group includes activators that directly impact cell signaling pathways and endocytic processes crucial for YMER's function. Compounds such as EGF enhance YMER's activity by stimulating or modulating key signaling pathways like EGF receptor signaling. This activation underscores YMER's involvement in intricate cellular signaling processes.
The second group includes activators that influence endocytic trafficking, a primary process in which YMER is implicated. Chlorpromazine, Dynasore, and Pitstop 2, by modulating clathrin-mediated endocytosis and dynamin-dependent pathways, indirectly enhance YMER's activity in endocytic processes. Monensin, Nocodazole, and Cytochalasin D, through their effects on lysosomal acidification, microtubule dynamics, and actin polymerization, respectively, contribute to the modulation of YMER's function in cellular trafficking. Genistein's role as a tyrosine kinase inhibitor further illustrates the interconnectedness of signaling pathways and endocytic processes in regulating YMER's activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $60.00 $108.00 | 21 | |
Chlorpromazine, known to inhibit clathrin-mediated endocytosis, can indirectly affect YMER's function in endocytic trafficking. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynasore, a GTPase inhibitor for dynamin, can enhance YMER's activity by influencing dynamin-dependent endocytic pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can modulate YMER function by affecting tyrosine kinase-dependent signaling pathways. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin, an ionophore that disrupts lysosomal acidification, can indirectly enhance YMER's function in endocytic pathways. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole, a microtubule depolymerizing agent, can influence YMER's role in cellular trafficking and signal transduction. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D, an inhibitor of actin polymerization, can enhance YMER's activity by affecting actin-dependent endocytic processes. | ||||||
Pitstop 2 | 1419320-73-2 | sc-507418 | 10 mg | $360.00 | ||
Pitstop 2, an inhibitor of clathrin-mediated endocytosis, can indirectly influence YMER's function in endocytic trafficking. | ||||||