WWC2 Activators
WW and C2 domain containing 2 (WWC2) activators belong to a specialized class of chemical compounds designed to modulate the activity of the WWC2 protein. WWC2, also known as KIBRA (Kidney and Brain Protein), is a crucial regulator of various cellular processes, including cell growth, proliferation, and tissue development. These activators are specifically engineered to interact with WWC2, either directly or indirectly, in order to influence its functions within the cell.
t the molecular level, WWC2 activators often possess structural motifs that enable them to bind to specific regions of the WWC2 protein, typically within its WW and C2 domains. These domains are essential for mediating protein-protein interactions and membrane targeting, respectively, making them prime targets for pharmacological intervention. By engaging with WWC2, these activators can modulate downstream signaling pathways and cellular responses associated with WWC2 function. This modulation can lead to a wide range of cellular effects, depending on the specific context and downstream partners of WWC2. The development and utilization of WWC2 activators in scientific research provide valuable insights into the intricate signaling networks that govern cell behavior and tissue development. By manipulating WWC2 activity, researchers can gain a deeper understanding of the molecular mechanisms underlying various cellular processes.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Calcium ions directly increase WWC2 activity through calcium-dependent signaling cascades and activate pathways associated with WWC2. | ||||||
Phorbol-12,13-dibutyrate | 37558-16-0 | sc-202285 | 1 mg | $124.00 | 3 | |
PDBu activates protein kinase C (PKC), indirectly impacting WWC2 activity by modulating downstream signaling pathways connected to WWC2. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases cyclic AMP (cAMP) levels, indirectly influencing WWC2 activity by affecting signaling pathways that intersect with WWC2 signaling. | ||||||
Calmodulin (human), (recombinant) | 73298-54-1 | sc-471287 | 1 mg | $300.00 | ||
Calmodulin can directly or indirectly increases WWC2 activity by modulating calcium-dependent signaling pathways associated with WWC2. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine, a protein kinase inhibitor, indirectly increases WWC2 activity by investigating the role of kinases in WWC2 regulation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin indirectly increases WWC2 activity by influencing signaling pathways in which WWC2 may be involved, as a phosphoinositide 3-kinase (PI3K) inhibitor. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a phosphatase inhibitor, which, when used in studies, can indirectly increase WWC2 activity by exploring the role of protein phosphatases. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
Neomycin, inhibiting phospholipase C (PLC), indirectly increases WWC2 activity by affecting downstream signaling pathways involving WWC2. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
GF 109203X, a selective PKC inhibitor, indirectly increases WWC2 activity by modulating PKC, which may intersect with WWC2 signaling pathways. | ||||||