Date published: 2025-10-15

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WRN Antibodies

Santa Cruz Biotechnology features a diverse variety of WRN monoclonal antibodies for advanced research in molecular biology. WRN monoclonal antibodies support multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). WRN protein, a member of the RecQ helicase family, maintains genomic stability through DNA repair, replication, and recombination processes. Mutations in the WRN gene are associated with Werner syndrome, a disorder characterized by premature aging and increased cancer risk, highlighting WRN's significance in cellular health and longevity. Understanding WRN function is essential for elucidating mechanisms underlying genomic instability and age-related diseases. Research into WRN's role in DNA metabolism continues to reveal new insights about cellular aging and cancer development. Investigating WRN's interactions with other proteins helps explain how cells maintain genomic integrity. Studies of WRN expression patterns across different tissues provide valuable information about its biological functions. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance our understanding of WRN's role in human health and disease.

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WRN Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

WRN Antibody (D-6)

sc-376182mouse IgG1 κ1133-1432 (h)WB, IP, IF, ELISAh
4
(2)

WRN Antibody (F-33)

sc-101110mouse IgG2a κ1322-1433 (h)WB, IP, IF, ELISAm, r, h

new

(2)

WRN CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

WRN CRISPR/Cas9 KO Plasmid (h)

sc-401860hGene KnockoutGFP
3
(0)

WRN HDR Plasmid (h)

sc-401860-HDRhHomology Directed RepairPuromycin
3
(0)

WRN Double Nickase Plasmid (h)

sc-401860-NIChGene KnockoutPuromycin
3
(0)

WRN Double Nickase Plasmid (h2)

sc-401860-NIC-2hGene KnockoutPuromycin
3
(0)

WRN CRISPR/Cas9 KO Plasmid (m)

sc-423724mGene KnockoutGFP0
(0)

WRN HDR Plasmid (m)

sc-423724-HDRmHomology Directed RepairPuromycin0
(0)

WRN Double Nickase Plasmid (m)

sc-423724-NICmGene KnockoutPuromycin0
(0)

WRN Double Nickase Plasmid (m2)

sc-423724-NIC-2mGene KnockoutPuromycin0
(0)

WRN CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

WRN CRISPR Activation Plasmid (h)

sc-401860-ACThGene ActivationPuro, Blast, Hygro
3
(0)

WRN CRISPR Activation Plasmid (h2)

sc-401860-ACT-2hGene ActivationPuro, Blast, Hygro
3
(0)

WRN Lentiviral Activation Particles (h)

sc-401860-LAChGene ActivationPuro, Blast, Hygro
3
(0)

WRN Lentiviral Activation Particles (h2)

sc-401860-LAC-2hGene ActivationPuro, Blast, Hygro
3
(0)

WRN CRISPR Activation Plasmid (m)

sc-423724-ACTmGene ActivationPuro, Blast, Hygro0
(0)

WRN CRISPR Activation Plasmid (m2)

sc-423724-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

WRN Lentiviral Activation Particles (m)

sc-423724-LACmGene ActivationPuro, Blast, Hygro0
(0)

WRN Lentiviral Activation Particles (m2)

sc-423724-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

WRN siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

WRN siRNA (h)

sc-36843hGene SilencingN/A
4
(1)

WRN shRNA Plasmid (h)

sc-36843-SHhGene SilencingPuromycin
4
(1)

WRN shRNA (h) Lentiviral Particles

sc-36843-VhGene SilencingPuromycin
4
(1)

WRN siRNA (m)

sc-36844mGene SilencingN/A
2
(0)

WRN shRNA Plasmid (m)

sc-36844-SHmGene SilencingPuromycin
2
(0)

WRN shRNA (m) Lentiviral Particles

sc-36844-VmGene SilencingPuromycin
2
(0)