When considering the realm of VWC2L activators, a nuanced perspective emerges on how intricate cellular processes interlink, particularly concerning the BMP signaling pathway and neuron differentiation. Interestingly, the use of K252a, DMH1, LDN-193189, and Dorsomorphin, all of which either antagonize or inhibit BMP signaling in various ways, adds layers of complexity to how VWC2L's role might be modulated in the BMP pathway. This underscores the balancing act of activators and in ensuring the pathway's proper functioning, hinting at the nuances in VWC2L's role within this cellular mechanism.
On the other front, VWC2L's role in neuron differentiation surfaces with compounds such as Retinoic Acid, Valproic Acid, Indirubin, Isobavachalcone, Bay K 8644, and BDNF. These compounds, each with their distinct cellular influences, emphasize neuron differentiation. Retinoic Acid, for instance, has long been recognized for its potent effects on neuron differentiation. In contrast, BDNF, a neurotrophin, has a profound impact on neuron survival and differentiation. By using these chemicals, it's conceivable to explore how VWC2L, which is predicted to act upstream of neuron differentiation, might be influenced, offering a deeper understanding of its role within this cellular process.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid can promote neuron differentiation, potentially influencing VWC2L, which acts upstream in this process. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid promotes neuronal differentiation. Given VWC2L's role in this process, the chemical can influence its activity. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $126.00 $210.00 $488.00 | 19 | |
K252a is known to inhibit BMP signaling, and by modulating this pathway, it may indirectly affect VWC2L's regulatory role. | ||||||
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $209.00 $312.00 $620.00 $1026.00 | 2 | |
DMH1 is a BMP type I receptors inhibitor. It impacts BMP signaling, potentially influencing VWC2L's function. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
LDN-193189 is a selective BMP type I receptor inhibitor. By altering BMP signaling, it might modulate VWC2L's activity. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
Dorsomorphin inhibits BMP type I receptors, impacting BMP signaling, and therefore might have an effect on VWC2L's function. | ||||||
Indirubin | 479-41-4 | sc-201531 sc-201531A | 5 mg 25 mg | $112.00 $515.00 | 4 | |
Indirubin promotes neuronal differentiation and may thereby influence VWC2L, which is upstream in this process. | ||||||
Isobavachalcone | 20784-50-3 | sc-202666 | 1 mg | $213.00 | 1 | |
Isobavachalcone has shown to promote neuron differentiation, potentially influencing VWC2L's role in neuron differentiation. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $82.00 $192.00 $801.00 | ||
Bay K 8644 enhances neuronal differentiation, suggesting its potential to influence VWC2L's function in this process. | ||||||