Date published: 2025-12-17

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VWC2L Activators

When considering the realm of VWC2L activators, a nuanced perspective emerges on how intricate cellular processes interlink, particularly concerning the BMP signaling pathway and neuron differentiation. Interestingly, the use of K252a, DMH1, LDN-193189, and Dorsomorphin, all of which either antagonize or inhibit BMP signaling in various ways, adds layers of complexity to how VWC2L's role might be modulated in the BMP pathway. This underscores the balancing act of activators and in ensuring the pathway's proper functioning, hinting at the nuances in VWC2L's role within this cellular mechanism.

On the other front, VWC2L's role in neuron differentiation surfaces with compounds such as Retinoic Acid, Valproic Acid, Indirubin, Isobavachalcone, Bay K 8644, and BDNF. These compounds, each with their distinct cellular influences, emphasize neuron differentiation. Retinoic Acid, for instance, has long been recognized for its potent effects on neuron differentiation. In contrast, BDNF, a neurotrophin, has a profound impact on neuron survival and differentiation. By using these chemicals, it's conceivable to explore how VWC2L, which is predicted to act upstream of neuron differentiation, might be influenced, offering a deeper understanding of its role within this cellular process.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid can promote neuron differentiation, potentially influencing VWC2L, which acts upstream in this process.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic acid promotes neuronal differentiation. Given VWC2L's role in this process, the chemical can influence its activity.

K-252a

99533-80-9sc-200517
sc-200517B
sc-200517A
100 µg
500 µg
1 mg
$126.00
$210.00
$488.00
19
(2)

K252a is known to inhibit BMP signaling, and by modulating this pathway, it may indirectly affect VWC2L's regulatory role.

DMH-1

1206711-16-1sc-361171
sc-361171B
sc-361171A
sc-361171C
10 mg
25 mg
50 mg
100 mg
$209.00
$312.00
$620.00
$1026.00
2
(0)

DMH1 is a BMP type I receptors inhibitor. It impacts BMP signaling, potentially influencing VWC2L's function.

4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

1062368-24-4sc-476297
5 mg
$240.00
(0)

LDN-193189 is a selective BMP type I receptor inhibitor. By altering BMP signaling, it might modulate VWC2L's activity.

BML-275

866405-64-3sc-200689
sc-200689A
5 mg
25 mg
$94.00
$348.00
69
(1)

Dorsomorphin inhibits BMP type I receptors, impacting BMP signaling, and therefore might have an effect on VWC2L's function.

Indirubin

479-41-4sc-201531
sc-201531A
5 mg
25 mg
$112.00
$515.00
4
(1)

Indirubin promotes neuronal differentiation and may thereby influence VWC2L, which is upstream in this process.

Isobavachalcone

20784-50-3sc-202666
1 mg
$213.00
1
(1)

Isobavachalcone has shown to promote neuron differentiation, potentially influencing VWC2L's role in neuron differentiation.

(±)-Bay K 8644

71145-03-4sc-203324
sc-203324A
sc-203324B
1 mg
5 mg
50 mg
$82.00
$192.00
$801.00
(0)

Bay K 8644 enhances neuronal differentiation, suggesting its potential to influence VWC2L's function in this process.