Date published: 2025-9-11

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Vmn2r8 Inhibitors

The chemical class described as Vmn2r8 Inhibitors encompasses a broad spectrum of compounds that, through their action on various cellular signaling pathways and processes, possess the capacity to indirectly modulate the activity or expression of Vmn2r8. These compounds target a range of mechanisms, including kinase activity modulation, calcium signaling alteration, and cAMP pathway modulation. By influencing these signaling mechanisms, the compounds offer a means to explore the biological functions of Vmn2r8 and its role in pheromone detection and signaling within the vomeronasal system.

This indirect approach to the modulation of Vmn2r8 activity highlights the complex and interconnected nature of cellular signaling networks, where alterations in one part of the system can have cascading effects on others, thereby influencing the function of specific proteins such as Vmn2r8. The strategic selection of these compounds provides a toolkit for probing the signaling pathways and processes that underlie Vmn2r8's function, facilitating insights into the regulatory mechanisms that govern its activity. Through such exploration, the inhibitors not only enhance our understanding of Vmn2r8's role in sensory signaling but also exemplify the broader principles of signal transduction and cellular communication. This methodology underscores the potential of chemical biology to dissect intricate signaling networks, offering a window into the dynamic interplay of signals that drive cellular responses and behaviors.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

Activates protein kinase C, potentially modulating GPCR-mediated signaling pathways relevant to Vmn2r8.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Increases intracellular cAMP levels, potentially altering cAMP-dependent pathways that could intersect with Vmn2r8 signaling.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$27.00
$52.00
37
(1)

Modulates store-operated calcium entry, potentially influencing calcium signaling pathways relevant to Vmn2r8's function.

BAPTA/AM

126150-97-8sc-202488
sc-202488A
25 mg
100 mg
$138.00
$449.00
61
(2)

Chelates intracellular calcium, potentially affecting calcium-dependent signaling processes linked to Vmn2r8 activity.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

Inhibits MEK1/2, potentially impacting MAPK/ERK signaling pathways that Vmn2r8 may be involved in.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

p38 MAPK inhibitor, could modulate stress and inflammatory signaling pathways associated with Vmn2r8.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

PI3K inhibitor, affecting AKT signaling pathways that could intersect with Vmn2r8's signaling mechanisms.

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$92.00
$223.00
30
(1)

Src family kinase inhibitor, potentially altering kinase-mediated signaling pathways relevant to Vmn2r8.

KN-93

139298-40-1sc-202199
1 mg
$178.00
25
(1)

Inhibits CaMKII, could influence calcium-dependent signaling pathways relevant to Vmn2r8.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

MEK inhibitor, potentially affects MAPK/ERK signaling pathways that Vmn2r8 could be part of.