The chemical class described as Vmn2r8 Inhibitors encompasses a broad spectrum of compounds that, through their action on various cellular signaling pathways and processes, possess the capacity to indirectly modulate the activity or expression of Vmn2r8. These compounds target a range of mechanisms, including kinase activity modulation, calcium signaling alteration, and cAMP pathway modulation. By influencing these signaling mechanisms, the compounds offer a means to explore the biological functions of Vmn2r8 and its role in pheromone detection and signaling within the vomeronasal system.
This indirect approach to the modulation of Vmn2r8 activity highlights the complex and interconnected nature of cellular signaling networks, where alterations in one part of the system can have cascading effects on others, thereby influencing the function of specific proteins such as Vmn2r8. The strategic selection of these compounds provides a toolkit for probing the signaling pathways and processes that underlie Vmn2r8's function, facilitating insights into the regulatory mechanisms that govern its activity. Through such exploration, the inhibitors not only enhance our understanding of Vmn2r8's role in sensory signaling but also exemplify the broader principles of signal transduction and cellular communication. This methodology underscores the potential of chemical biology to dissect intricate signaling networks, offering a window into the dynamic interplay of signals that drive cellular responses and behaviors.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C, potentially modulating GPCR-mediated signaling pathways relevant to Vmn2r8. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP levels, potentially altering cAMP-dependent pathways that could intersect with Vmn2r8 signaling. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
Modulates store-operated calcium entry, potentially influencing calcium signaling pathways relevant to Vmn2r8's function. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Chelates intracellular calcium, potentially affecting calcium-dependent signaling processes linked to Vmn2r8 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK1/2, potentially impacting MAPK/ERK signaling pathways that Vmn2r8 may be involved in. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor, could modulate stress and inflammatory signaling pathways associated with Vmn2r8. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, affecting AKT signaling pathways that could intersect with Vmn2r8's signaling mechanisms. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor, potentially altering kinase-mediated signaling pathways relevant to Vmn2r8. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibits CaMKII, could influence calcium-dependent signaling pathways relevant to Vmn2r8. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor, potentially affects MAPK/ERK signaling pathways that Vmn2r8 could be part of. |