Vmn2r68 Inhibitors
Vmn2r68 can act through various mechanisms to alter the receptor's function. Benzamidine, for instance, operates as a serine protease inhibitor, likely affecting the activation or processing of Vmn2r68, which may require protease activity for its ligand interactions or receptor modulation. Similarly, the potassium channel blocker Tetraethylammonium (TEA) can modify membrane potential and cell excitability, essential for the signaling mediated by Vmn2r68, thus influencing its activity. Methiothepin, as a non-selective serotonin antagonist, and Chlorpromazine, which antagonizes multiple neurotransmitter receptors, including those for dopamine and serotonin, disrupt neuronal signaling pathways. This disruption can indirectly affect Vmn2r68's function by altering the neural network's balance that governs its activity.
Quinidine's role as a voltage-gate sodium channel blocker means it can intervene in the action potential propagation within neurons, which may indirectly influence the pathways that involve Vmn2r68. Phentolamine and Yohimbine, both targeting adrenergic receptors, but with Phentolamine being non-selective and Yohimbine specifically antagonizing alpha-2 adrenergic receptors, can impact adrenergic signaling. This, in turn, influences the neurotransmitter environment of Vmn2r68. Propranolol, by antagonizing beta-adrenergic receptors, modifies sympathetic nervous system activities, which could shape the physiological context in which Vmn2r68 functions. Atropine inhibits muscarinic acetylcholine receptors, potentially affecting parasympathetic nerve activity and thus Vmn2r68's role in the nervous system. Lastly, Ondansetron's activity as a serotonin 5-HT3 receptor antagonist, Nifedipine's calcium channel blocking action, and Amiloride's inhibition of sodium channels can all contribute to an altered cellular signaling environment, which can influence Vmn2r68's function by changing neurotransmitter release, neuronal excitability, and ionic balances crucial for its operation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Benzamidine | 618-39-3 | sc-233933 | 10 g | $292.00 | 1 | |
Benzamidine is a known serine protease inhibitor. Vmn2r68, being a chemosensory receptor, may rely on protease activity for activation or inactivation of certain ligands or in the processing of the receptor itself. Benzamidine could potentially inhibit this protease activity, thereby inhibiting the functional activation of Vmn2r68. | ||||||
Tetraethylammonium chloride | 56-34-8 | sc-202834 | 25 g | $45.00 | 2 | |
Tetraethylammonium (TEA) is a known potassium channel blocker. By blocking potassium channels, TEA can alter membrane potential and cellular excitability, which may be necessary for the proper functioning of Vmn2r68 as it may rely on membrane potentials for signal transduction. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine is an antagonist of various neurotransmitter receptors, including dopaminergic, serotonergic, and adrenergic receptors. By inhibiting these receptors, it could disrupt the signaling balance in the brain, potentially inhibiting Vmn2r68 activity indirectly through altered neural circuitry that regulates Vmn2r68 expression or function. | ||||||
Quinidine | 56-54-2 | sc-212614 | 10 g | $104.00 | 3 | |
Quinidine is a voltage-gate sodium channel blocker. It can inhibit the action potential propagation in neurons, which might indirectly affect the signaling pathways that Vmn2r68 is involved in, leading to its functional inhibition. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
Propranolol is a beta-adrenergic receptor antagonist. It can alter the sympathetic nervous system activity, which may affect the function of Vmn2r68 indirectly by modifying the physiological context in which Vmn2r68 operates. | ||||||
Atropine | 51-55-8 | sc-252392 | 5 g | $204.00 | 2 | |
Atropine is a competitive antagonist for the muscarinic acetylcholine receptors. By blocking these receptors, it can alter parasympathetic nerve activity, which might in turn influence the function of Vmn2r68 in the nervous system. | ||||||
Yohimbine hydrochloride | 65-19-0 | sc-204412 sc-204412A sc-204412B | 1 g 5 g 25 g | $51.00 $171.00 $530.00 | 2 | |
Yohimbine is an alpha-2 adrenergic receptor antagonist. By blocking these receptors, yohimbine may increase the release of noradrenaline, which could inhibit Vmn2r68 activity by altering the neurotransmitter environment that Vmn2r68 is exposed to. | ||||||
Ondansetron | 99614-02-5 | sc-201127 sc-201127A | 10 mg 50 mg | $82.00 $333.00 | 1 | |
Ondansetron is a serotonin 5-HT3 receptor antagonist. It can affect the gastrointestinal and central nervous system functions, which may indirectly inhibit Vmn2r68 by disrupting the signaling pathways that Vmn2r68 is a part of. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine is a calcium channel blocker. By inhibiting calcium influx, it can affect neurotransmitter release and neuronal excitability. This alteration in calcium signaling could indirectly inhibit the function of Vmn2r68. | ||||||
Amiloride | 2609-46-3 | sc-337527 | 1 g | $296.00 | 7 | |
Amiloride is a sodium channel blocker and diuretic. It inhibits epithelial sodium channels, which can influence ionic balances and cellular signaling. This could indirectly inhibit Vmn2r68 by altering the ionic environment that is crucial for its function. | ||||||