UPII Activators

UPII Activators, as listed here, are primarily compounds that can potentially influence the function or expression of Uroplakin II indirectly. These compounds are not direct activators but could play a role in modulating the cellular processes and signaling pathways involved in urothelial cell biology. Compounds like Retinoic Acid, EGF, and Vitamin D3 are involved in cellular growth and differentiation, which are key processes in the maintenance and function of urothelial cells. Their impact on urothelial cells could extend to the regulation of UPII expression.

Growth factors such as FGF-7, TGF-β1, and KGF are important in epithelial cell proliferation and tissue remodeling. They might influence UPII expression by affecting the growth and differentiation status of urothelial cells. PGE2 and Hyaluronic Acid, involved in inflammation and repair processes, could have an impact on urothelial cells and, consequently, on UPII expression, especially in contexts of urothelial injury or disease. Hormones like Estrogen and Testosterone, known to influence urothelial biology, could potentially affect UPII expression due to their regulatory roles in tissue-specific biology.