TRP1 Inhibitors
Common TRP1 Inhibitors include, but are not limited to Ellagic Acid, Dihydrate CAS 476-66-4, 4-tert-Butylcatechol CAS 98-29-3, Resorcinol CAS 108-46-3, Cinnamic acid CAS 621-82-9 and L-Ascorbic acid, free acid CAS 50-81-7.
TRP1 inhibitors belong to a specific chemical class of compounds designed to target and inhibit the activity of Tyrosinase-related protein 1 (TRP1). TRP1, also known as dopachrome tautomerase (DCT), is a melanogenic enzyme involved in melanin biosynthesis. It plays a critical role in the conversion of dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), an intermediate in the melanin synthesis pathway. Melanin is the pigment responsible for determining the color of the skin, hair, and eyes.
TRP1 inhibitors work by specifically targeting the TRP1 protein, interfering with its catalytic activity and its role in melanin production. By doing so, these inhibitors may modulate the melanin biosynthesis pathway and impact the accumulation of melanin pigments in melanocytes and other pigment-producing cells. Research into TRP1 and its inhibitors is ongoing to unravel their precise mechanisms of action and explore their implications in cellular processes. The study of TRP1 inhibitors represents an intriguing area of research, contributing to a deeper understanding of the intricate mechanisms governing melanin synthesis and its impact on pigmentation in different tissues and organisms.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $57.00 $93.00 $240.00 $713.00 | 8 | |
Inhibits TRP1 activity through its antioxidant properties, reducing reactive oxygen species production. | ||||||
4-tert-Butylcatechol | 98-29-3 | sc-254726 sc-254726A | 100 g 500 g | $45.00 $143.00 | ||
Acts as a competitive inhibitor of TRP1 by interfering with the enzyme's active site. | ||||||
Resorcinol | 108-46-3 | sc-203371 sc-203371A sc-203371B | 100 g 500 g 25 g | $56.00 $205.00 $30.00 | 1 | |
Blocks the catalytic activity of TRP1, reducing melanin synthesis. | ||||||
Cinnamic acid | 621-82-9 | sc-337631 | 1 g | $560.00 | ||
Modulates TRP1 activity by interfering with the enzyme's catalytic site. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Reduces TRP1 activity through its antioxidant properties. | ||||||
Glycolic acid solution | 79-14-1 | sc-215102 sc-215102A | 25 g 500 g | $38.00 $60.00 | ||
Disrupts TRP1 function by interfering with enzyme-substrate interactions. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Acts as an allosteric inhibitor of TRP1, affecting the enzyme's conformation and activity. | ||||||
Ferulic acid | 1135-24-6 | sc-204753 sc-204753A sc-204753B sc-204753C sc-204753D | 5 g 25 g 100 g 500 g 1 kg | $42.00 $62.00 $153.00 $552.00 $988.00 | 10 | |
Inhibits TRP1 through multiple mechanisms, including antioxidant activity and enzyme inactivation. | ||||||
Vanillic acid | 121-34-6 | sc-251422 sc-251422A | 25 g 50 g | $44.00 $88.00 | 2 | |
Modulates TRP1 enzymatic activity by binding to the enzyme's active site. | ||||||
4-Hexylresorcinol | 136-77-6 | sc-238860 | 25 g | $69.00 | 2 | |
Reduces TRP1 activity, thereby inhibiting melanin synthesis. | ||||||