4-Hexylresorcinol is an inhibitor of transglutaminase-2 in KB cells. Studies indicate that 4-Hexylresorcinol reduces DNA oxidative damage in human lymphocytes. The combination of 4-Hexylresorcinol and Cisplatin (sc-200896) has been shown to inhibit tumor growth, cell growth, and KB cell viability. Alternate studies suggest that 4-Hexylresorcinol is a potent irreversible inhibitor of polyphenol oxidase (PPO) activity. Furthermore, 4-Hexylresorcinol is a mixed-type inhibitor which influences the apparent V(max) and K(m) values of the inhibitor by binding preferentially to the oxy form of PPO.
1. Arias, E., et al. 2007. J. Food Sci. 72: C464-C470. PMID: 18034705 2. Kim, S.G., et al. 2011. Oncol. Rep. 25: 1597-1602. PMID: 21424127
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65-67° C (lit.)
333-335° C (lit.)
1.036 g/cm3 at 20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
UN 3077, Class 9, Packing group III
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