Items 11 to 17 of 17 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Imiquimod can indirectly activate TRIM49 by triggering interferon production, which is a key regulator of TRIM49 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can downregulate protein synthesis and affect cellular growth pathways. If TRIM49's function is associated with proteins regulated by mTOR pathways, rapamycin could indirectly inhibit TRIM49 by reducing the levels of these regulatory proteins. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
Poly(I:C) can indirectly activate TRIM49 by simulating viral RNA, triggering the interferon response, which in turn may activate TRIM49. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
A MDM2 antagonist that stabilizes p53, leading to cell cycle arrest and apoptosis. If TRIM49 is involved in pathways regulated by p53, the stabilization of p53 by Nutlin-3 could result in a decrease in TRIM49 activity due to altered cell cycle dynamics and apoptotic processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor that prevents the activation of downstream kinases. If TRIM49 activity is modulated by p38 MAPK, inhibition by SB203580 could lead to a decrease in TRIM49's functional activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which is involved in stress response. By inhibiting JNK, SP600125 could affect signaling pathways that regulate TRIM49, leading to an indirect inhibition of its activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A selective inhibitor of MEK, which blocks the activation of MAPK/ERK. If the function or stability of TRIM49 is influenced by the MAPK/ERK pathway, PD98059 could indirectly inhibit TRIM49 by impeding pathway activation. | ||||||