Items 11 to 12 of 12 total
Display:
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Alternariol monomethyl ether | 26894-49-5 | sc-206070 sc-206070A | 1 mg 5 mg | $260.00 $610.00 | 1 | |
Alternariol monomethyl ether acts as a topoisomerase II alpha inhibitor by engaging with the enzyme's active site, inducing conformational changes that hinder its catalytic function. Its structural features promote specific hydrogen bonding and hydrophobic interactions, enhancing binding stability. The compound's unique electronic properties influence the reaction kinetics, leading to a modulation of DNA topology and impacting the overall cellular processes involving DNA replication and repair. | ||||||
Gatifloxacin-d4 | sc-218565 | 1 mg | $360.00 | |||
Gatifloxacin-d4 interacts with topoisomerase II alpha through a unique mechanism that stabilizes the enzyme's closed conformation, effectively obstructing its activity. The compound's isotopic labeling enhances its detection in biochemical assays, allowing for precise tracking of molecular interactions. Its distinct steric and electronic characteristics facilitate selective binding, influencing the enzyme's dynamics and altering the equilibrium of DNA supercoiling, thereby affecting nucleic acid metabolism. |