Date published: 2026-4-24

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TIRAP Antibodies

Santa Cruz Biotechnology delivers a wide array of TIRAP monoclonal antibodies for research focused on understanding TIRAP's role in immune signaling pathways. TIRAP Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).TIRAP, or Toll-interleukin 1 receptor (TIR) domain-containing adapter protein, plays a crucial role in the innate immune response by mediating signaling pathways for Toll-like receptors (TLRs). TIRAP is essential for activating downstream signaling cascades that lead to the production of pro-inflammatory cytokines, thereby influencing the body's defense mechanisms against pathogens. Understanding TIRAP's function is vital for elucidating immune responses and developing therapeutic strategies for immune-related diseases. Researchers can investigate TIRAP's involvement in various cellular processes, from signal transduction to inflammatory responses. TIRAP research has significant implications for understanding autoimmune disorders, inflammatory conditions, and potential therapeutic interventions. Current studies focus on mapping TIRAP's interactions with other proteins in the signaling cascade and its regulation during immune responses. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of immune system regulation and contribute to the development of new therapeutic approaches.

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TIRAP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TIRAP Antibody (A-11)

sc-166149mouse IgG2a κFL (h)WB, IP, IF, ELISAh
3
(2)

TIRAP Antibody (B-3)

sc-166151mouse IgG1 κFL (h)WB, IP, IF, ELISAh
1
(1)

TIRAP Antibody (C-7)

sc-166150mouse IgG1 κFL (h)WB, IP, IF, ELISAh

new

(1)

TIRAP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TIRAP CRISPR/Cas9 KO Plasmid (h)

sc-402650hGene KnockoutGFP0
(0)

TIRAP HDR Plasmid (h)

sc-402650-HDRhHomology Directed RepairPuromycin0
(0)

TIRAP Double Nickase Plasmid (m)

sc-431178-NICmGene KnockoutPuromycin0
(0)

TIRAP Double Nickase Plasmid (m2)

sc-431178-NIC-2mGene KnockoutPuromycin0
(0)

TIRAP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TIRAP CRISPR Activation Plasmid (h)

sc-402650-ACThGene ActivationPuro, Blast, Hygro0
(0)

TIRAP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TIRAP siRNA (h)

sc-42932hGene SilencingN/A
2
(0)

TIRAP shRNA Plasmid (h)

sc-42932-SHhGene SilencingPuromycin
2
(0)

TIRAP shRNA (h) Lentiviral Particles

sc-42932-VhGene SilencingPuromycin
2
(0)

TIRAP siRNA (m)

sc-44740mGene SilencingN/A
2
(0)

TIRAP shRNA Plasmid (m)

sc-44740-SHmGene SilencingPuromycin
2
(0)

TIRAP shRNA (m) Lentiviral Particles

sc-44740-VmGene SilencingPuromycin
2
(0)