Date published: 2026-4-1

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TIM-3 Antibodies

Santa Cruz Biotechnology offers a broad range of TIM-3 monoclonal antibodies for research focused on understanding this important immune checkpoint protein. TIM-3 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TIM-3, or T-cell immunoglobulin and mucin-domain containing-3, functions as a critical regulator of immune responses, particularly in T-cell exhaustion and tolerance. TIM-3 plays a significant role in modulating the immune system's response to tumors and chronic infections, making it a key target for therapeutic interventions in cancer and autoimmune diseases. Research into TIM-3 expression and activity can reveal important mechanisms of immune regulation. Understanding TIM-3's molecular interactions helps identify potential strategies for enhancing anti-tumor immunity. Investigating TIM-3 signaling pathways provides valuable insights into immune checkpoint biology. Exploring TIM-3's role in different cell types advances knowledge of immune system regulation. Santa Cruz Biotechnology monoclonal antibodies enable researchers to conduct detailed studies of TIM-3, contributing to breakthroughs in immunology and cancer research.

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TIM-3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TIM-3 Antibody (182H2B)

sc-517632mouse IgG2b κ(h)WB, FCMh

new

(0)

TIM-3 CRISPR Knockout, HDR and Double Nickase Plasmids

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TIM-3 CRISPR/Cas9 KO Plasmid (h)

sc-416365hGene KnockoutGFP0
(0)

TIM-3 HDR Plasmid (h)

sc-416365-HDRhHomology Directed RepairPuromycin0
(0)

TIM-3 Double Nickase Plasmid (h)

sc-416365-NIChGene KnockoutPuromycin0
(0)

TIM-3 Double Nickase Plasmid (h2)

sc-416365-NIC-2hGene KnockoutPuromycin0
(0)

TIM-3 CRISPR/Cas9 KO Plasmid (m)

sc-431363mGene KnockoutGFP0
(0)

TIM-3 CRISPR Activation Products

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TIM-3 CRISPR Activation Plasmid (h)

sc-416365-ACThGene ActivationPuro, Blast, Hygro0
(0)

TIM-3 CRISPR Activation Plasmid (h2)

sc-416365-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TIM-3 Lentiviral Activation Particles (h)

sc-416365-LAChGene ActivationPuro, Blast, Hygro0
(0)

TIM-3 CRISPR Activation Plasmid (m)

sc-431363-ACTmGene ActivationPuro, Blast, Hygro0
(0)

TIM-3 CRISPR Activation Plasmid (m2)

sc-431363-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

TIM-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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TIM-3 siRNA (h)

sc-72034hGene SilencingN/A
3
(0)

TIM-3 shRNA Plasmid (h)

sc-72034-SHhGene SilencingPuromycin
3
(0)

TIM-3 shRNA (h) Lentiviral Particles

sc-72034-VhGene SilencingPuromycin
3
(0)

TIM-3 siRNA (m)

sc-72015mGene SilencingN/A0
(1)

TIM-3 shRNA Plasmid (m)

sc-72015-SHmGene SilencingPuromycin0
(1)

TIM-3 shRNA (m) Lentiviral Particles

sc-72015-VmGene SilencingPuromycin0
(1)