THAP3 Activators constitute a specialized class of chemical compounds or molecules that have garnered attention within the field of molecular biology and cellular research. These activators are specifically designed or identified with the aim of modulating the activity of the THAP3 gene. THAP3, or Thanatos-Associated Protein 3, is a protein-coding gene found in humans and various organisms. It encodes a protein containing a THAP (Thanatos-Associated Protein) domain, known for its role in DNA binding and transcriptional regulation.
The study of THAP3 activators is intriguing because it provides researchers with a means to explore the precise role of the THAP3 gene in cellular physiology and molecular mechanisms related to gene expression and regulation. Activation of THAP3 can offer valuable insights into its potential involvement in processes such as DNA binding, chromatin remodeling, and transcriptional control, contributing to our understanding of how genes are controlled and regulated within cells. By manipulating the activity of THAP3 through these activators, scientists aim to gain a deeper understanding of the intricate molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, THAP3 activators serve as valuable tools for researchers dedicated to unraveling the complex molecular mechanisms that underlie cellular biology and the specific roles played by individual genes in these processes, particularly within the context of transcriptional regulation and gene expression control.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing cAMP levels, which might enhance the transcription of genes, including THAP3. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid acts through retinoic acid receptors to regulate gene expression, which may upregulate THAP3. | ||||||
all-trans Retinal | 116-31-4 | sc-210778A sc-210778 | 250 mg 1 g | $126.00 $372.00 | 7 | |
All-trans retinal, a vitamin A derivative, can influence gene transcription, potentially affecting THAP3 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is a glucocorticoid that can regulate gene expression via the glucocorticoid receptor, potentially impacting THAP3. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences glycogen synthase kinase-3 (GSK-3) activity, which is involved in various signaling pathways that may upregulate THAP3. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which may lead to downstream effects on gene regulation, including THAP3 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling, which can modulate transcriptional programs, potentially affecting THAP3 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Butyrate is an HDAC inhibitor, which can cause epigenetic changes that may increase the transcription of THAP3. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and may influence the transcription of various genes, potentially including THAP3. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
DMSO is often used as a solvent, but it can also influence cellular processes and gene expression, potentially impacting THAP3. | ||||||