SYDE2 Activators
SYDE2, or Synapse Defective 1 Rho GTPase Homolog 2, is a gene that encodes a protein involved in the regulation of actin cytoskeleton dynamics. The actin cytoskeleton is a crucial component of cellular structure and plays a vital role in various cellular processes, including cell shape maintenance, migration, and division.The protein encoded by SYDE2 belongs to the Rho GTPase family, which is known for its role in actin cytoskeleton organization. Rho GTPases act as molecular switches, cycling between an active GTP-bound state and an inactive GDP-bound state. They regulate a wide range of cellular functions by controlling the assembly and disassembly of actin filaments.
SYDE2 is particularly important in the regulation of actin cytoskeleton remodeling. This remodeling is essential for numerous cellular activities, such as morphological changes during cell movement and the formation of cell protrusions like lamellipodia and filopodia. These processes are fundamental in various physiological contexts, including wound healing, immune responses, and embryonic development.In addition to its role in cytoskeletal dynamics, SYDE2 is implicated in other cellular functions. It may be involved in cell signaling pathways that influence cell proliferation, differentiation, and survival. These functions are crucial in maintaining normal cellular physiology and can have implications in disease processes when dysregulated.Alterations in the expression or function of SYDE2 have links to various pathological conditions, including cancer and neurological disorders.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, Y-27632 can modulate RhoA signaling, potentially influencing SYDE2's regulatory role. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
An inhibitor of Cdc42, ML141 can influence cytoskeletal dynamics, potentially impacting SYDE2 activity. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin polymerization, Cytochalasin D might indirectly affect SYDE2 activity by altering cytoskeletal dynamics. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
An inhibitor of actin polymerization, Latrunculin A can impact cell signaling and cytoskeletal organization, potentially influencing SYDE2. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
An inhibitor of myosin II, Blebbistatin affects cytoskeletal dynamics and could indirectly impact SYDE2. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
A stabilizer of actin filaments, Jasplakinolide can influence cytoskeletal dynamics, potentially affecting SYDE2. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, Paclitaxel might indirectly influence SYDE2's role in cell signaling and morphology. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule depolymerizing agent, Nocodazole can affect cell morphology and signaling, potentially impacting SYDE2. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Another microtubule destabilizing agent, Colchicine might influence SYDE2 activity by altering cytoskeletal dynamics. | ||||||