Date published: 2026-4-24

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SUR-1 Antibodies

Santa Cruz Biotechnology offers a broad range of SUR-1 monoclonal antibodies for advanced research in cellular signaling and metabolism. SUR-1 monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SUR-1, also known as the sulfonylurea receptor 1, plays a critical role in regulating insulin secretion and glucose homeostasis. It is a key component of the ATP-sensitive potassium channels in pancreatic beta cells, influencing cellular excitability and insulin release in response to glucose levels. Understanding the function of SUR-1 is essential for elucidating mechanisms underlying diabetes and other metabolic disorders. SUR-1 monoclonal antibodies enable researchers to investigate cellular responses to glucose fluctuations and examine the molecular mechanisms of insulin secretion. Studying SUR-1 expression patterns and interactions provides valuable insights into pancreatic beta cell function and dysfunction. Research utilizing SUR-1 monoclonal antibodies contributes to developing targeted treatments for metabolic diseases. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of diabetes and metabolic regulation.

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SUR-1 Antibodies

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SUR-1 Antibody (3G5)

sc-293436mouse IgG2a κ611-710 (h)WB, IP, ELISAh
1
(1)

SUR-1 CRISPR Knockout, HDR and Double Nickase Plasmids

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SUR-1 CRISPR/Cas9 KO Plasmid (m)

sc-423217mGene KnockoutGFP0
(0)

SUR-1 HDR Plasmid (m)

sc-423217-HDRmHomology Directed RepairPuromycin0
(0)

SUR-1 CRISPR Activation Products

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SUR-1 CRISPR Activation Plasmid (m)

sc-423217-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SUR-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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SUR-1 siRNA (h)

sc-42634hGene SilencingN/A0
(0)

SUR-1 shRNA Plasmid (h)

sc-42634-SHhGene SilencingPuromycin0
(0)

SUR-1 shRNA (h) Lentiviral Particles

sc-42634-VhGene SilencingPuromycin0
(0)

SUR-1 siRNA (m)

sc-42635mGene SilencingN/A0
(0)

SUR-1 shRNA Plasmid (m)

sc-42635-SHmGene SilencingPuromycin0
(0)

SUR-1 shRNA (m) Lentiviral Particles

sc-42635-VmGene SilencingPuromycin0
(0)