SUG1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Meradine | 7390-62-7 | sc-211792 | 10 mg | $330.00 | ||
Meradine is a potent acid halide characterized by its ability to engage in nucleophilic acyl substitution reactions. Its electrophilic carbonyl group facilitates rapid interactions with amines and alcohols, leading to the formation of stable amides and esters. The compound exhibits unique reactivity patterns, influenced by steric and electronic factors, which can modulate reaction rates. Additionally, Meradine's solubility in organic solvents enhances its versatility in synthetic applications, allowing for diverse chemical transformations. | ||||||
4-(Ethylthio)-3′-fluorobenzhydrol | 844683-71-2 | sc-336149 | 5 g | $2403.00 | ||
4-(Ethylthio)-3'-fluorobenzhydrol is a distinctive acid halide known for its selective reactivity in electrophilic aromatic substitution. The presence of the ethylthio group enhances its nucleophilicity, allowing for unique interactions with various substrates. Its fluorine atom introduces intriguing electronic effects, influencing reaction pathways and kinetics. This compound's solubility in polar solvents further broadens its potential for diverse synthetic methodologies, enabling complex transformations. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Binds to the 26S proteasome with high affinity and specificity, inhibiting its proteolytic function, which indirectly affects the function of SUG1. | ||||||
Carfilzomib | 868540-17-4 | sc-396755 | 5 mg | $40.00 | ||
Irreversible proteasome inhibitor, binds selectively to the proteasome's active site threonine and could affect SUG1 as part of the proteasome complex. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Reversible proteasome inhibitor that can affect the activity of SUG1 by inhibiting the degradation process of ubiquitinated proteins. | ||||||
Ixazomib | 1072833-77-2 | sc-489103 sc-489103A | 10 mg 50 mg | $311.00 $719.00 | ||
Selective and reversible proteasome inhibitor that would affect SUG1 activity by stabilizing proteins marked for degradation. | ||||||
Oprozomib | 935888-69-0 | sc-477447 | 2.5 mg | $280.00 | ||
An oral proteasome inhibitor that, upon activation, inhibits the CT-L activity of the proteasome, potentially affecting SUG1 function within the complex. | ||||||
Delanzomib, free base | 847499-27-8 | sc-396774 sc-396774A | 5 mg 10 mg | $160.00 $300.00 | ||
A proteasome inhibitor that would impact SUG1 by inhibiting the breakdown of ubiquitinated proteins. | ||||||
Epoxomicin | 134381-21-8 | sc-201298C sc-201298 sc-201298A sc-201298B | 50 µg 100 µg 250 µg 500 µg | $134.00 $215.00 $440.00 $496.00 | 19 | |
A natural product that irreversibly inhibits proteasome activity, thus potentially affecting SUG1 activity associated with proteasomal degradation. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $165.00 $575.00 | 60 | |
Specific inhibitor of the proteasome that can indirectly affect SUG1 by inhibiting the degradation of polyubiquitinated proteins. | ||||||