Items 71 to 80 of 202 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2′-Deoxycytidine acts as a pivotal stem cell reagent by inhibiting DNA methyltransferases, leading to the demethylation of cytosine residues. This process reactivates silenced genes associated with pluripotency and differentiation. Its unique ability to alter epigenetic landscapes facilitates the transition of somatic cells to a more stem-like state, enhancing self-renewal and promoting lineage-specific differentiation pathways. This dynamic modulation of gene expression is crucial for stem cell maintenance. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $120.00 | 5 | |
Chaetocin serves as a distinctive stem cell reagent by targeting histone methyltransferases, particularly those involved in the regulation of H3K9 methylation. This inhibition disrupts repressive chromatin states, promoting a more open and accessible genome. By modulating histone modifications, Chaetocin influences transcriptional activity, fostering an environment conducive to stem cell pluripotency and enhancing the potential for cellular reprogramming and differentiation. Its unique mechanism underscores its role in epigenetic regulation. | ||||||
Fluoxetine hydrochloride | 56296-78-7 | sc-201125 sc-201125A sc-201125B sc-201125C | 50 mg 250 mg 1 g 5 g | $75.00 $209.00 $399.00 $849.00 | 14 | |
Fluoxetine hydrochloride acts as a notable stem cell reagent by modulating serotonin signaling pathways, which are crucial for cellular communication and differentiation. Its interaction with specific receptors can influence intracellular signaling cascades, promoting cellular plasticity. Additionally, Fluoxetine's ability to alter gene expression profiles through epigenetic mechanisms enhances stem cell maintenance and self-renewal, making it a valuable tool in stem cell research and regenerative biology. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $66.00 $278.00 | 6 | |
Imiquimod serves as a distinctive stem cell reagent by engaging toll-like receptors, particularly TLR7, which initiates a cascade of immune responses and influences stem cell fate. This interaction enhances the production of cytokines, promoting a microenvironment conducive to stem cell proliferation and differentiation. Furthermore, Imiquimod's ability to modulate the expression of key transcription factors can drive lineage specification, making it a compelling agent in stem cell studies. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $153.00 $520.00 | 4 | |
GSK-3 Inhibitor XVI functions as a notable stem cell reagent by selectively inhibiting glycogen synthase kinase-3, a pivotal regulator in various signaling pathways. This inhibition alters the phosphorylation state of critical proteins, thereby influencing Wnt signaling and enhancing stem cell self-renewal. Additionally, its unique interaction with β-catenin stabilizes this protein, promoting transcriptional activity that drives pluripotency and differentiation in stem cell populations. | ||||||
GANT61 | 500579-04-4 | sc-202630 sc-202630A sc-202630B | 1 mg 5 mg 10 mg | $63.00 $128.00 $200.00 | 6 | |
GANT61 serves as a significant stem cell reagent by specifically targeting and inhibiting the activity of the transcription factor GLI, a key component of the Hedgehog signaling pathway. This selective inhibition disrupts downstream gene expression, leading to altered cellular fate decisions. GANT61's unique ability to modulate chromatin dynamics and influence epigenetic modifications further enhances its role in promoting stem cell maintenance and differentiation processes. | ||||||
CTPB | 586976-24-1 | sc-202558 sc-202558A | 1 mg 5 mg | $58.00 $162.00 | 4 | |
CTPB is a versatile stem cell reagent that acts as a potent modulator of cellular signaling pathways. It interacts with specific protein targets, influencing their conformation and activity, which in turn affects downstream signaling cascades. CTPB's unique ability to alter cellular microenvironments and promote specific gene expression profiles makes it a valuable tool in stem cell research. Its kinetic properties allow for precise control over cellular responses, facilitating the study of stem cell behavior and differentiation. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $36.00 $110.00 $400.00 | ||
BIX01294 hydrochloride is a specialized stem cell reagent known for its selective inhibition of histone methyltransferases, particularly those involved in epigenetic regulation. By disrupting specific protein interactions, it alters chromatin structure and gene expression dynamics, promoting pluripotency in stem cells. Its unique mechanism of action enables researchers to dissect complex regulatory networks, providing insights into stem cell maintenance and differentiation processes. | ||||||
HDAC6 Inhibitor Inhibitor | 1045792-66-2 | sc-223877 sc-223877A | 500 µg 1 mg | $62.00 $86.00 | 5 | |
HDAC6 Inhibitor is a potent stem cell reagent that selectively targets histone deacetylase 6, influencing cellular acetylation states. By modulating the acetylation of non-histone proteins, it impacts various signaling pathways, including those related to cytoskeletal dynamics and stress responses. This selective inhibition fosters an environment conducive to stem cell self-renewal and differentiation, allowing for a deeper understanding of cellular plasticity and developmental biology. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $37.00 $77.00 $184.00 $510.00 $1224.00 $5814.00 | 8 | |
Niclosamide serves as a versatile stem cell reagent by disrupting mitochondrial function and altering metabolic pathways. Its unique ability to inhibit the Wnt/β-catenin signaling pathway influences stem cell fate decisions and promotes differentiation. Additionally, Niclosamide modulates reactive oxygen species levels, which can affect cellular signaling and survival. This multifaceted interaction with cellular metabolism and signaling networks enhances the study of stem cell behavior and regenerative processes. | ||||||