Date published: 2025-12-21

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SRp75 Activators

SRp75 activators encompass a class of molecules that are known for their ability to enhance the activity or expression of SRp75. SRp75, a part of the serine/arginine-rich (SR) protein family, is integral to the process of splicing - a fundamental part of gene expression where introns are removed from pre-mRNA transcripts and exons are connected to create the mature mRNA. SRp75, and SR proteins in general, have roles in both constitutive and alternative splicing, the latter of which enables the generation of diverse protein products from a single gene. Thus, activators of SRp75 exert influence on this critical aspect of gene expression.

SRp75 activators can operate through a variety of mechanisms. Some may interact directly with SRp75, enhancing its ability to participate in the splicing process. Others may influence the expression of SRp75 by impacting the transcription or translation of the SRp75 gene, thereby increasing the cellular level of SRp75. There are also compounds that might affect upstream or downstream signaling pathways that indirectly modulate SRp75 activity. For instance, some SRp75 activators might influence how cells respond to stress or damage, which could, in turn, have a bearing on the role of SRp75 in these responses. Despite the differences in their specific mechanisms of action, all SRp75 activators share the common characteristic of enhancing the activity or expression of SRp75 in one way or another. These compounds provide an invaluable toolset for studying the complex process of splicing and the crucial role of SRp75 within it.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$58.00
$83.00
$140.00
$242.00
38
(2)

Nocodazole might induce SRp75 expression as part of its broad effects on cellular microtubule dynamics.

Tamoxifen

10540-29-1sc-208414
2.5 g
$256.00
18
(2)

Tamoxifen might influence SRp75 expression due to its selective estrogen receptor modulatory properties.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

Thapsigargin might modulate SRp75 expression due to its interactions with endoplasmic reticulum stress response.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

5-Aza-2′-Deoxycytidine might influence SRp75 expression through its effects on DNA hypomethylation.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Camptothecin could potentially upregulate SRp75 due to its action on topoisomerase I inhibition.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Mitomycin C could potentially induce SRp75 expression as part of its effects on DNA crosslinking.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$38.00
$58.00
$102.00
$202.00
8
(1)

Geldanamycin could potentially induce SRp75 expression due to its potent effects on heat shock protein 90 (Hsp90).

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Suberoylanilide Hydroxamic Acid might enhance SRp75 expression via its histone deacetylase (HDAC) inhibitory properties.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic Acid could potentially induce SRp75 expression due to its effects on HDAC inhibition and GABAergic signaling.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin could potentially upregulate SRp75 through its role in cellular antioxidant response.