Date published: 2026-5-2

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SQSTM1 Antibodies

Santa Cruz Biotechnology delivers a wide array of SQSTM1 monoclonal antibodies for research focused on understanding SQSTM1 protein functions. SQSTM1 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).SQSTM1, also known as p62, is a multifunctional protein that plays a critical role in cellular processes such as autophagy, inflammation, and the regulation of protein degradation. SQSTM1 functions as a signaling hub that links ubiquitinated proteins to the autophagic machinery, thereby influencing cellular homeostasis and response to stress. Research on SQSTM1 has revealed its significance in various diseases, including neurodegenerative disorders and cancer, where dysregulation can have significant implications. Understanding SQSTM1's role in cellular pathways continues to provide valuable insights into disease mechanisms and potential therapeutic strategies. Investigating SQSTM1's interactions with other proteins helps reveal new aspects of cellular regulation and stress response. Exploring SQSTM1's involvement in autophagy pathways contributes to our understanding of cellular quality control mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific knowledge and contribute to breakthrough discoveries in cell biology and disease research.

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SQSTM1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SQSTM1/p62 Antibody (D-3)

sc-28359mouse IgG1 κ151-440 (h)WB, IP, IF, IHC(P), ELISAh
609
(68)

SQSTM1/p62 Antibody (A-6)

sc-48402mouse IgG1 κ151-440 (h)WB, IP, IF, IHC(P), ELISAm, r, h
87
(19)

SQSTM1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SQSTM1/p62 CRISPR/Cas9 KO Plasmid (h)

sc-400099hGene KnockoutGFP0
(7)

SQSTM1/p62 HDR Plasmid (h)

sc-400099-HDRhHomology Directed RepairPuromycin0
(7)

SQSTM1/p62 Double Nickase Plasmid (h)

sc-400099-NIChGene KnockoutPuromycin0
(7)

SQSTM1/p62 Double Nickase Plasmid (h2)

sc-400099-NIC-2hGene KnockoutPuromycin0
(7)

SQSTM1/p62 CRISPR/Cas9 KO Plasmid (m)

sc-422075mGene KnockoutGFP0
(1)

SQSTM1/p62 HDR Plasmid (m)

sc-422075-HDRmHomology Directed RepairPuromycin0
(1)

SQSTM1/p62 Double Nickase Plasmid (m)

sc-422075-NICmGene KnockoutPuromycin0
(1)

SQSTM1/p62 Double Nickase Plasmid (m2)

sc-422075-NIC-2mGene KnockoutPuromycin0
(1)

SQSTM1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SQSTM1/p62 CRISPR Activation Plasmid (h)

sc-400099-ACThGene ActivationPuro, Blast, Hygro0
(7)

SQSTM1/p62 Lentiviral Activation Particles (h)

sc-400099-LAChGene ActivationPuro, Blast, Hygro0
(7)

SQSTM1/p62 CRISPR Activation Plasmid (m)

sc-422075-ACTmGene ActivationPuro, Blast, Hygro0
(1)

SQSTM1/p62 CRISPR Activation Plasmid (m2)

sc-422075-ACT-2mGene ActivationPuro, Blast, Hygro0
(1)

SQSTM1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SQSTM1/p62 siRNA (h)

sc-29679hGene SilencingN/A
48
(1)

SQSTM1/p62 shRNA Plasmid (h)

sc-29679-SHhGene SilencingPuromycin
48
(1)

SQSTM1/p62 shRNA (h) Lentiviral Particles

sc-29679-VhGene SilencingPuromycin
48
(1)

SQSTM1/p62 siRNA (m)

sc-29828mGene SilencingN/A
12
(0)

SQSTM1/p62 shRNA Plasmid (m)

sc-29828-SHmGene SilencingPuromycin
12
(0)

SQSTM1/p62 shRNA (m) Lentiviral Particles

sc-29828-VmGene SilencingPuromycin
12
(0)