Date published: 2026-3-3

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SPP Antibodies

Santa Cruz Biotechnology features a diverse variety of SPP Antibodies for the specific detection and analysis of SPP (Sphingosine-1-phosphate phosphatase). SPP Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). SPP plays a crucial role in regulating sphingosine-1-phosphate levels, which are essential for numerous cellular processes, including cell proliferation, migration, and survival. Dysregulation of SPP has been implicated in various diseases, including cancer and cardiovascular disorders, making research into SPP and its interactions vital for understanding these conditions. Researchers can explore SPP expression patterns across different tissue types and cellular compartments. Advanced visualization techniques enable detailed mapping of SPP distribution and localization within cells. Understanding SPP regulation mechanisms provides insights into potential therapeutic targets for disease treatment. Santa Cruz Biotechnology monoclonal antibodies for SPP support researchers worldwide in advancing scientific understanding of cellular signaling pathways and disease mechanisms.

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SPP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SPPL2a Antibody (1C7)

sc-293375mouse IgG1 κ31-129 (h)WB, IP, ELISAm, r, h

new

(1)

SPP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPP CRISPR/Cas9 KO Plasmid (m)

sc-420752mGene KnockoutGFP0
(0)

SPP HDR Plasmid (m)

sc-420752-HDRmHomology Directed RepairPuromycin0
(0)

SPPL2b CRISPR/Cas9 KO Plasmid (h)

sc-405646hGene KnockoutGFP
1
(1)

SPPL3 CRISPR/Cas9 KO Plasmid (h)

sc-414174hGene KnockoutGFP0
(0)

SPP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPP CRISPR Activation Plasmid (h)

sc-405271-ACThGene ActivationPuro, Blast, Hygro0
(0)

SPPL2b CRISPR Activation Plasmid (h)

sc-405646-ACThGene ActivationPuro, Blast, Hygro
1
(1)

SPP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SPP siRNA (h)

sc-45549hGene SilencingN/A
1
(0)

SPP shRNA Plasmid (h)

sc-45549-SHhGene SilencingPuromycin
1
(0)

SPP shRNA (h) Lentiviral Particles

sc-45549-VhGene SilencingPuromycin
1
(0)

SPP siRNA (m)

sc-45550mGene SilencingN/A0
(0)

SPP shRNA Plasmid (m)

sc-45550-SHmGene SilencingPuromycin0
(0)

SPP shRNA (m) Lentiviral Particles

sc-45550-VmGene SilencingPuromycin0
(0)

SPPL2a siRNA (h)

sc-76570hGene SilencingN/A0
(0)

SPPL2a shRNA Plasmid (h)

sc-76570-SHhGene SilencingPuromycin0
(0)

SPPL2a shRNA (h) Lentiviral Particles

sc-76570-VhGene SilencingPuromycin0
(0)

SPPL2a siRNA (m)

sc-76571mGene SilencingN/A0
(0)

SPPL2a shRNA Plasmid (m)

sc-76571-SHmGene SilencingPuromycin0
(0)

SPPL2a shRNA (m) Lentiviral Particles

sc-76571-VmGene SilencingPuromycin0
(0)

SPPL2b siRNA (h)

sc-97546hGene SilencingN/A0
(0)

SPPL2b shRNA Plasmid (h)

sc-97546-SHhGene SilencingPuromycin0
(0)

SPPL2b shRNA (h) Lentiviral Particles

sc-97546-VhGene SilencingPuromycin0
(0)

SPPL2b siRNA (m)

sc-153780mGene SilencingN/A0
(0)

SPPL2b shRNA Plasmid (m)

sc-153780-SHmGene SilencingPuromycin0
(0)

SPPL2b shRNA (m) Lentiviral Particles

sc-153780-VmGene SilencingPuromycin0
(0)

SPPL3 siRNA (h)

sc-96234hGene SilencingN/A0
(0)

SPPL3 shRNA Plasmid (h)

sc-96234-SHhGene SilencingPuromycin0
(0)

SPPL3 shRNA (h) Lentiviral Particles

sc-96234-VhGene SilencingPuromycin0
(0)

SPPL3 siRNA (m)

sc-153781mGene SilencingN/A0
(0)

SPPL3 shRNA Plasmid (m)

sc-153781-SHmGene SilencingPuromycin0
(0)

SPPL3 shRNA (m) Lentiviral Particles

sc-153781-VmGene SilencingPuromycin0
(0)