Date published: 2025-9-11

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Sphingolipids

Santa Cruz Biotechnology now offers a broad range of sphingolipids for use in various applications. Sphingolipids are a class of complex lipids containing a sphingoid base backbone, which are essential components of cell membranes and play crucial roles in cellular signaling and structural integrity. These compounds are significant in scientific research due to their involvement in numerous biological processes and their impact on cell function and health. In biochemistry and cell biology, sphingolipids are studied to understand their role in membrane structure, signaling pathways, and their influence on cell behavior, including apoptosis, proliferation, and differentiation. Researchers utilize sphingolipids to investigate mechanisms of diseases associated with lipid metabolism disorders and to explore potential targets for novel strategies, although not in a clinical context. In neuroscience, sphingolipids are crucial for studying the function and organization of the nervous system, given their role in myelin sheath formation and neuron function. Environmental scientists study sphingolipids to understand their role in cellular responses to environmental stressors and their potential as biomarkers for environmental monitoring. Additionally, sphingolipids are employed in the development of advanced materials and nanotechnology, where their unique structural properties can be harnessed for creating biomimetic materials and drug delivery systems. Analytical chemists use sphingolipids in techniques such as mass spectrometry and chromatography to analyze lipid compositions and understand lipidomics, the large-scale study of pathways and networks of cellular lipids in biological systems. The broad applications of sphingolipids in scientific research underscore their importance in advancing our knowledge of fundamental biological processes and driving innovations across multiple disciplines. View detailed information on our available sphingolipids by clicking on the product name.

Items 61 to 64 of 64 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

C-12 NBD-dihydro-Ceramide

474943-05-0sc-221389
sc-221389A
1 mg
5 mg
$334.00
$1503.00
(0)

C-12 NBD-dihydro-Ceramide is a sphingolipid distinguished by its hydrophobic tail and fluorescent NBD group, which enables visualization in biological systems. This compound participates in lipid metabolism and cellular signaling, influencing pathways such as apoptosis and cell differentiation. Its unique structure promotes interactions with membrane proteins, potentially altering lipid bilayer dynamics and facilitating the formation of specialized membrane domains, thereby impacting cellular communication and function.

Phytosphingosine

554-62-1sc-201385
sc-201385A
5 mg
25 mg
$100.00
$419.00
4
(1)

Phytosphingosine, a key sphingolipid, plays a crucial role in cellular signaling and membrane dynamics. Its unique long-chain structure allows for specific interactions with membrane proteins, influencing lipid bilayer fluidity and stability. This compound is involved in the regulation of apoptosis and inflammation through distinct signaling pathways. Additionally, its ability to form hydrogen bonds enhances its integration into lipid membranes, contributing to cellular integrity and function.

Ganglioside GM2 sodium salt

19600-01-2sc-500856
1 mg
$681.00
(0)

Ganglioside GM2 sodium salt is a complex sphingolipid characterized by its unique oligosaccharide headgroup, which plays a crucial role in cell recognition and signaling. This compound is involved in modulating membrane fluidity and stability, influencing the organization of lipid rafts. Its interactions with specific receptors can trigger intracellular signaling cascades, affecting cellular responses. Additionally, GM2's structural diversity allows for distinct binding affinities, impacting its biological roles in various cellular contexts.

N-(NBD-Aminocaproyl)sphinganine

sc-301239
50 µg
$42.00
(0)

N-(NBD-Aminocaproyl)sphinganine is a specialized sphingolipid that features a unique NBD (nitrobenzoxadiazole) moiety, enhancing its fluorescent properties for tracking and imaging in biological systems. This compound participates in lipid metabolism and can influence the formation of lipid bilayers, affecting membrane dynamics. Its ability to form hydrogen bonds and engage in hydrophobic interactions contributes to its role in cellular signaling pathways and membrane organization, highlighting its significance in lipid biochemistry.