Date published: 2025-9-11

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Sphingolipids

Santa Cruz Biotechnology now offers a broad range of sphingolipids for use in various applications. Sphingolipids are a class of complex lipids containing a sphingoid base backbone, which are essential components of cell membranes and play crucial roles in cellular signaling and structural integrity. These compounds are significant in scientific research due to their involvement in numerous biological processes and their impact on cell function and health. In biochemistry and cell biology, sphingolipids are studied to understand their role in membrane structure, signaling pathways, and their influence on cell behavior, including apoptosis, proliferation, and differentiation. Researchers utilize sphingolipids to investigate mechanisms of diseases associated with lipid metabolism disorders and to explore potential targets for novel strategies, although not in a clinical context. In neuroscience, sphingolipids are crucial for studying the function and organization of the nervous system, given their role in myelin sheath formation and neuron function. Environmental scientists study sphingolipids to understand their role in cellular responses to environmental stressors and their potential as biomarkers for environmental monitoring. Additionally, sphingolipids are employed in the development of advanced materials and nanotechnology, where their unique structural properties can be harnessed for creating biomimetic materials and drug delivery systems. Analytical chemists use sphingolipids in techniques such as mass spectrometry and chromatography to analyze lipid compositions and understand lipidomics, the large-scale study of pathways and networks of cellular lipids in biological systems. The broad applications of sphingolipids in scientific research underscore their importance in advancing our knowledge of fundamental biological processes and driving innovations across multiple disciplines. View detailed information on our available sphingolipids by clicking on the product name.

Items 11 to 20 of 64 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lignoceric ceramide

34435-05-7sc-202694
5 mg
$130.00
(0)

Lignoceric ceramide is a long-chain sphingolipid characterized by its unique fatty acid composition, which influences membrane fluidity and stability. This ceramide plays a crucial role in cellular signaling by participating in the formation of lipid rafts, enhancing protein interactions and signaling cascades. Its distinct hydrophobic properties facilitate the organization of membrane microdomains, impacting cellular processes such as apoptosis and stress response. Additionally, lignoceric ceramide is involved in the biosynthesis of complex sphingolipids, contributing to cellular architecture and function.

Ceramide phosphorylethanolamine

sc-300332
5 mg
$403.00
(0)

Ceramide phosphorylethanolamine is a sphingolipid that features a phosphorylethanolamine head group, which enhances its hydrophilicity and influences membrane dynamics. This unique structure promotes interactions with membrane proteins, facilitating signal transduction pathways. Its role in modulating lipid bilayer properties allows for the formation of specialized membrane domains, impacting cellular communication and response mechanisms. Additionally, it participates in the synthesis of bioactive lipids, contributing to cellular homeostasis.

C17 Sphingosine

6918-48-5sc-223852
sc-223852A
5 mg
25 mg
$219.00
$617.00
1
(0)

C17 Sphingosine is a key sphingolipid characterized by its long hydrocarbon chain, which contributes to its hydrophobic nature and influences membrane fluidity. This lipid plays a crucial role in the formation of lipid rafts, enhancing the organization of membrane proteins and lipids. Its unique structure allows for specific interactions with various signaling molecules, modulating cellular responses and contributing to the regulation of apoptosis and cell growth.

MSDH-C

144474-37-3sc-203145
1 mg
$133.00
(0)

MSDH-C is a distinctive sphingolipid that features a complex hydrophobic backbone, facilitating its integration into lipid bilayers. Its unique structural attributes enable it to engage in specific molecular interactions, influencing membrane dynamics and stability. MSDH-C participates in intricate signaling pathways, affecting cellular communication and response mechanisms. Additionally, its reactivity as an acid halide allows for versatile modifications, impacting lipid metabolism and cellular architecture.

SEW2871

256414-75-2sc-203251
sc-203251A
5 mg
10 mg
$37.00
$52.00
1
(0)

SEW2871 is a specialized sphingolipid characterized by its unique hydrophobic structure, which enhances its affinity for membrane environments. This compound plays a crucial role in modulating lipid raft formation, thereby influencing protein localization and signaling cascades. Its reactivity as an acid halide allows for selective acylation reactions, facilitating the formation of diverse lipid species. These interactions contribute to the regulation of cellular processes and membrane integrity.

Sphingosylphosphorylcholine, D-erythro

1670-26-4sc-201384
10 mg
$400.00
1
(1)

Sphingosylphosphorylcholine, D-erythro, is a distinctive sphingolipid known for its dual role in cellular signaling and membrane dynamics. Its unique amphipathic nature promotes interactions with membrane proteins, influencing their conformation and activity. This compound participates in intricate signaling pathways, particularly in cell adhesion and migration. Additionally, its ability to form stable complexes with other lipids enhances membrane fluidity and organization, impacting cellular communication and response mechanisms.

DL-erythro-Dihydrosphingosine

3102-56-5sc-203018
sc-203018A
10 mg
100 mg
$158.00
$1025.00
(0)

DL-erythro-Dihydrosphingosine is a notable sphingolipid characterized by its structural versatility and role in lipid bilayer formation. Its hydrophobic tail facilitates integration into cellular membranes, influencing membrane curvature and stability. This compound is involved in the biosynthesis of complex sphingolipids, contributing to lipid raft formation and cellular compartmentalization. Its interactions with various proteins can modulate enzymatic activities and cellular responses, highlighting its importance in maintaining cellular homeostasis.

C8 Ceramine, D-erythro

170926-06-4sc-223854
sc-223854A
1 mg
5 mg
$119.00
$386.00
(0)

C8 Ceramine, D-erythro, is a distinctive sphingolipid known for its unique hydrophilic-hydrophobic balance, which enhances membrane fluidity and permeability. This compound plays a critical role in cellular signaling pathways, particularly in the modulation of apoptosis and cell differentiation. Its ability to form stable complexes with specific proteins can influence intracellular transport mechanisms, while its structural features allow for diverse interactions within lipid microdomains, impacting cellular communication and function.

Ganglioside GT1b, Trisialo, Triammonium Salt

sc-221661
1 mg
$400.00
1
(0)

Ganglioside GT1b, Trisialo, Triammonium Salt is a complex sphingolipid characterized by its intricate carbohydrate moieties, which facilitate specific interactions with cell surface receptors. This compound is integral to neuronal signaling, influencing synaptic plasticity and cell recognition processes. Its unique triammonium structure enhances solubility and stability in aqueous environments, promoting effective membrane incorporation and contributing to the formation of lipid rafts that organize signaling molecules.

3-O-Methylsphingomyelin

sc-205580
sc-205580A
1 mg
5 mg
$126.00
$520.00
1
(0)

3-O-Methylsphingomyelin is a specialized sphingolipid distinguished by its methylation at the 3-position of the sphingosine backbone, which alters its hydrophobic interactions and membrane dynamics. This modification influences lipid bilayer properties, enhancing membrane fluidity and stability. Its unique structure facilitates specific lipid-lipid and lipid-protein interactions, playing a crucial role in cellular signaling pathways and membrane organization, particularly in lipid raft formation.